Domenico Ribatti
University of Bari
965 Papers
6.1K Citations
Domenico Ribatti is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Biology. The author has an hindex of 96, co-authored 913 publications. Previous affiliations of Domenico Ribatti include University of Genoa & National Institutes of Health.
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Papers
The chick embryo chorioallantoic membrane as a model for in vivo research on angiogenesis.
TL;DR: Thanks to the CAM system, angiogenesis could be investigated in association with normal, inflammatory and tumor tissues, and soluble factors inducing angiogenic or anti-angiogenic effects could be identified.
Thalidomide Downregulates Angiogenic Genes in Bone Marrow Endothelial Cells of Patients With Active Multiple Myeloma
Angelo Vacca,Claudio Scavelli,Vittorio Montefusco,Giulia Di Pietro,Antonino Neri,Michela Mattioli,Silvio Bicciato,Beatrice Nico,Domenico Ribatti,Franco Dammacco,Paolo Corradini +10 more
TL;DR: Thalidomide markedly downregulates the genes in a dose-dependent fashion in active MMECs and KS cell line, but upregulates them or is ineffective in nonactive MM ECs, MG(u)ECs, NHL-ECS, and in HUVECs.
A model of study for human cancer: Spontaneous occurring tumors in dogs. Biological features and translation for new anticancer therapies
Girolamo Ranieri,Cosmo Damiano Gadaleta,Rosa Patruno,Nicola Zizzo,Maria Grazia Daidone,Mats G. Hansson,A. Paradiso,Domenico Ribatti +7 more
TL;DR: Biological data from dog tumors and comparative features with human tumors, and new therapeutic approaches translated from dog to human cancer are analyzed.
Order and disorder in the vascular network
Diego Guidolin,Beatrice Nico,Giuseppina Mazzocchi,Angelo Vacca,G. G. Nussdorfer,Domenico Ribatti +5 more
TL;DR: In this article, the authors presented a model for in vitro angiogenesis based on experiments performed with bovine aortic endothelial cells focusing on cellular network reorganization driven by cellular traction and showed that nonlinear mechanics and chemotactic cellular dynamics fit into a model able to reproduce with great accuracy the formation of vascular networks in vitro.
Angiogenesis in a human neuroblastoma xenograft model: mechanisms and inhibition by tumour-derived interferon- γ
Domenico Ribatti,Beatrice Nico,Annalisa Pezzolo,Angelo Vacca,Raffaella Meazza,R Cinti,Barbara Carlini,Federica Parodi,Vito Pistoia,Maria Valeria Corrias +9 more
TL;DR: The ACN/IFN-γ xenografts showed more terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling-positive human and murine endothelial cells, suggesting that inhibition of angiogenesis by IFn-γ was dependent on the induction of apoptosis, likely mediated by nitric oxide.