Domenico Ribatti
University of Bari
965 Papers
6.1K Citations
Domenico Ribatti is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Biology. The author has an hindex of 96, co-authored 913 publications. Previous affiliations of Domenico Ribatti include University of Genoa & National Institutes of Health.
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Papers
The CAM Assay as an Alternative In Vivo Model for Drug Testing.
TL;DR: Comparing advantages and disadvantages with the classical mouse xenograft model, exemplify established and innovative imaging techniques that are used in the CAM model, and give examples of its successful utilization for studying major hallmarks of cancer such as angiogenesis, proliferation, invasion, and metastasis.
Sir Frank Macfarlane Burnet and the clonal selection theory of antibody formation.
TL;DR: The clonal selection theory is a theory of antibody synthesis capable of bridging the gap between physiological findings, such as the kinetics of antibody production, self-tolerance and immunological memory on the one hand, and the newest ideas on synthesis of proteins, on the other.
Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma
Giuseppe Lucarelli,Vanessa Galleggiante,Monica Rutigliano,Francesca Sanguedolce,Simona Cagiano,Pantaleo Bufo,Gaetano Lastilla,Eugenio Maiorano,Domenico Ribatti,Andrea Giglio,Grazia Serino,Antonio Vavallo,Carlo Bettocchi,Francesco Paolo Selvaggi,Michele Battaglia,Pasquale Ditonno +15 more
TL;DR: The data suggest that oncogenic signaling pathways may promote ccRCC through rerouting the sugar metabolism, and blocking the flux through this pathway may serve as a novel therapeutic target.
Chicken chorioallantoic membrane angiogenesis model.
TL;DR: The chick embryo chorioallantoic membrane (CAM) is an extraembryonic membrane which serves as a gas exchange surface and its function is supported by a dense capillary network, which has been broadly used to study the morphofunctional aspects of the angiogenesis process in vivo and to investigate the efficacy and mechanisms of action of proangiogenic and antiangiogens natural and synthetic molecules.
Mast cells in breast cancer angiogenesis.
TL;DR: Mast cells might act as a new target for the adjuvant treatment of breast cancer through the selective inhibition of angiogenesis, tissue remodeling and tumor promoting molecules, allowing the secretion of cytotoxic cytokines and preventing mast cell mediated immune-suppression.