Domenico Ribatti
University of Bari
965 Papers
6.1K Citations
Domenico Ribatti is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Biology. The author has an hindex of 96, co-authored 913 publications. Previous affiliations of Domenico Ribatti include University of Genoa & National Institutes of Health.
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Papers
Perivascular astrocytes and endothelium in the development of the blood-brain barrier in the optic tectum of the chick embryo
Mirella Bertossi,Luisa Roncali,Beatrice Nico,Domenico Ribatti,Lucia Mancini,Daniela Virgintino,G. Fabiani,Antonella Guidazzoli +7 more
TL;DR: This investigation suggests a close relationship between the perivascular arrangement of glia and differentiation of the endothelium tight junctions and indicates that the morphofunctional maturation of the latter takes place progressively during the prenatal organogenesis of the chick central nervous system.
I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo
Giovanni Bernardini,Gaia Spinetti,Domenico Ribatti,Grazia Camarda,Lucia Morbidelli,Marina Ziche,Angela Santoni,Maurizio C. Capogrossi,Monica Napolitano +8 more
TL;DR: It is shown that I-309 binds to endothelial cells, stimulates chemotaxis and invasion of these cells, and enhances HUVEC differentiation into capillary-like structures in an in vitro Matrigel assay.
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 agree with progression of ovarian endometriomas.
Roberto Ria,Giuseppe Loverro,Angelo Vacca,Domenico Ribatti,Gennaro Cormio,Aldo M. Roccaro,Luigi Selvaggi +6 more
TL;DR: Changes in angiogenesis and expression of extracellular matrix‐degrading enzymes have been substantiated in tumour changeover and progression and are associated with tumour progression.
Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma.
Domenico Ribatti,Angelo Vacca,Beatrice Nico,Fabio Quondamatteo,Roberto Ria,M Minischetti,Andrea Marzullo,Rainer Herken,Luisa Roncali,Franco Dammacco +9 more
TL;DR: Immunohistochemical, cytochemical and ultrastructural data showed vivid angiogenesis and numerous mast cells in the bone marrow of patients with active multiple myeloma led us to hypothesize thatAngiogenesis parallels progression of MM, and that MCs participate in its induction via angiogenic factors in their secretory granules.
A VEGF-dependent autocrine loop mediates proliferation and capillarogenesis in bone marrow endothelial cells of patients with multiple myeloma
Roberto Ria,Angelo Vacca,Francesca Russo,Teresa Cirulli,Massimo Massaia,Patrizia Tosi,Michele Cavo,Diego Guidolin,Domenico Ribatti,Franco Dammacco +9 more
TL;DR: The findings as a whole suggest the existence of an autocrine loop of VEGF in multiple myeloma-associated EC, which would constitute an appropriate target for antiangiogenic management in MM.