Dirk Simon
German Cancer Research Center
12 Papers
54 Citations
Dirk Simon is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Intravoxel incoherent motion & Effective diffusion coefficient. The author has an hindex of 9, co-authored 12 publications.
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Papers
An in vivo verification of the intravoxel incoherent motion effect in diffusion-weighted imaging of the abdomen.
TL;DR: A vascular contribution to the diffusion weighted imaging measurement at low b values is verified and support the Intra Voxel Incoherent Motion‐theory.
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Differentiation of pancreas carcinoma from healthy pancreatic tissue using multiple b-values: comparison of apparent diffusion coefficient and intravoxel incoherent motion derived parameters.
Andreas Lemke,Frederik Bernd Laun,Miriam Klauss,Thomas J. Re,Dirk Simon,Stefan Delorme,Lothar R. Schad,Bram Stieltjes +7 more
TL;DR: The f value proved to be the best parameter for the differentiation between healthy pancreas and pancreatic cancer using the IVIM-approach, and showed more than a 10-fold higher significance level in distinguishing cancerous from normal tissue when compared with the ADCtot value.
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Diffusion‐weighted imaging for non‐invasive and quantitative monitoring of bone marrow infiltration in patients with monoclonal plasma cell disease: a comparative study with histology
Jens Hillengass,Tobias Bäuerle,Reiner Bartl,Mindaugas Andrulis,Fabienne McClanahan,Frederik Bernd Laun,Christian M. Zechmann,Rajiv Shah,Barbara Wagner-Gund,Dirk Simon,Christiane Heiss,Kai Neben,Anthony D. Ho,Heinz Peter Schlemmer,Hartmut Goldschmidt,Stefan Delorme,Bram Stieltjes +16 more
TL;DR: DWI enabled bone marrow infiltration to be monitored in a non‐invasive, quantitative way, suggesting that after further investigations on larger patient groups this might become an useful tool in the clinical work‐up to assess tumour burden.
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Intravoxel incoherent motion MRI for the differentiation between mass forming chronic pancreatitis and pancreatic carcinoma.
Miriam Klau,Andreas Lemke,Katharina Grünberg,Dirk Simon,Thomas J. Re,Mortiz N. Wente,Frederik Bernd Laun,Hans-Ulrich Kauczor,Stefan Delorme,Lars Grenacher,Bram Stieltjes +10 more
TL;DR: The perfusion fraction f proved to be the superior DWI-derived parameter for differentiation of mass-forming pancreatitis and pancreatic carcinoma and can be attributed mainly to differences in perfusion.
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Investigation of renal lesions by diffusion-weighted magnetic resonance imaging applying intravoxel incoherent motion-derived parameters--initial experience.
S. Rheinheimer,S. Rheinheimer,Bram Stieltjes,F. Schneider,Dirk Simon,Sascha Pahernik,Hans U. Kauczor,Peter Hallscheidt +7 more
TL;DR: IVIM imaging is able to provide reliable diffusion values in the human kidney and may enhance the accuracy of tumor diagnosis and the f value is promising for determining the histological subgroups.
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