Dirk Becker
University of Marburg
16 Papers
102 Citations
Dirk Becker is an academic researcher from University of Marburg. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 10, co-authored 14 publications. Previous affiliations of Dirk Becker include Bernhard Nocht Institute for Tropical Medicine.
Chat about Author
Papers
COVID-19 vaccine BNT162b1 elicits human antibody and T H 1 T cell responses.
Ugur Sahin,Alexander Muik,Evelyna Derhovanessian,Isabel Vogler,Lena M. Kranz,Mathias Vormehr,Alina Baum,Kristen E. Pascal,Jasmin Quandt,Daniel Maurus,Sebastian Brachtendorf,Verena Lörks,Julian Sikorski,Rolf Hilker,Dirk Becker,Ann Kathrin Eller,Jan Grützner,Carsten Boesler,Corinna Rosenbaum,Marie Cristine Kühnle,Ulrich Luxemburger,Alexandra Kemmer-Brück,David J. Langer,Martin Bexon,Stefanie Bolte,Katalin Karikó,Tania Palanche,Boris Fischer,Armin Schultz,Pei Yong Shi,Camila R. Fontes-Garfias,John L. Perez,Kena A. Swanson,Jakob Loschko,Ingrid L. Scully,Mark Cutler,Warren Kalina,Christos A. Kyratsous,David A. Cooper,Philip R. Dormitzer,Kathrin U. Jansen,Özlem Türeci +41 more
TL;DR: The robust RBD-specific antibody, T cell and favourable cytokine responses induced by the BNT162b1 mRNA vaccine suggest that it has the potential to protect against COVID-19 through multiple beneficial mechanisms.
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans.
Ugur Sahin,Alexander Muik,Isabel Vogler,Evelyna Derhovanessian,Lena M. Kranz,Mathias Vormehr,Jasmin Quandt,Nicole Bidmon,Alexander Ulges,Alina Baum,Kristen E. Pascal,Daniel Maurus,Sebastian Brachtendorf,Verena Lörks,Julian Sikorski,Peter Koch,Rolf Hilker,Dirk Becker,Ann Kathrin Eller,Jan Grützner,Manuel Tonigold,Carsten Boesler,Corinna Rosenbaum,Ludwig Heesen,Marie Cristine Kühnle,Asaf Poran,Jesse Z. Dong,Ulrich Luxemburger,Alexandra Kemmer-Brück,David J. Langer,Martin Bexon,Stefanie Bolte,Tania Palanche,Armin Schultz,Sybille Baumann,Azita J. Mahiny,Gábor Boros,Jonas Reinholz,Gábor Szabó,Katalin Karikó,Pei Yong Shi,Camila R. Fontes-Garfias,John L. Perez,Mark Cutler,David A. Cooper,Christos A. Kyratsous,Philip R. Dormitzer,Kathrin U. Jansen,Özlem Türeci +48 more
TL;DR: BNT162b2, a lipid nanoparticle (LNP) formulated nucleoside-modified messenger RNA (mRNA) that encodes the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S) stabilized in the prefusion conformation, has demonstrated 95% efficacy in preventing coronavalirus disease-19 (COVID-19)1 as mentioned in this paper.
Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa
Miles W. Carroll,David A. Matthews,Julian A. Hiscox,Michael J. Elmore,Georgios Pollakis,Andrew Rambaut,Roger Hewson,Isabel García-Dorival,Joseph Akoi Bore,Raymond Koundouno,Saïd Abdellati,Babak Afrough,John Aiyepada,Patience Akhilomen,Danny Asogun,Barry Atkinson,Marlis Badusche,Amadou Bah,Simon R. Bate,Jan Baumann,Dirk Becker,Beate Becker-Ziaja,Anne Bocquin,Benny Borremans,Andrew Bosworth,Jan Peter Boettcher,Angela Cannas,Fabrizio Carletti,Concetta Castilletti,Simon Clark,Francesca Colavita,Sandra Diederich,Adomeh Donatus,Sophie Duraffour,Deborah U. Ehichioya,Heinz Ellerbrok,Maria Dolores Fernandez-Garcia,Alexandra Fizet,Erna Fleischmann,Sophie Gryseels,Antje Hermelink,Julia Hinzmann,Ute Hopf-Guevara,Yemisi Ighodalo,Lisa J. Jameson,Anne Kelterbaum,Zoltán Kis,Stefan Kloth,Claudia Kohl,Miša Korva,Annette Kraus,Eeva Kuisma,Andreas Kurth,Britta Liedigk,Christopher H. Logue,Anja Lüdtke,Piet Maes,James McCowen,Stéphane Mély,Marc Mertens,Silvia Meschi,Benjamin Meyer,Janine Michel,Peter Molkenthin,César Muñoz-Fontela,Doreen Muth,Edmund N. C. Newman,Didier Ngabo,Lisa Oestereich,Jennifer Okosun,Thomas Olokor,Racheal Omiunu,Emmanuel Omomoh,Elisa Pallasch,Bernadett Pályi,Jasmine Portmann,Thomas Pottage,Catherine Pratt,Simone Priesnitz,Serena Quartu,Julie C. F. Rappe,Johanna Repits,Martin Richter,Martin Rudolf,Andreas Sachse,Kristina Maria Schmidt,Gordian Schudt,Thomas Strecker,Ruth Thom,Stephen Thomas,Ekaete Alice Tobin,Howard Tolley,Jochen Trautner,Tine Vermoesen,Inês Vitoriano,Matthias Wagner,Svenja Wolff,Constanze Yue,Maria Rosaria Capobianchi,Birte Kretschmer,Yper Hall,John Kenny,Natasha Y. Rickett,Gytis Dudas,Cordelia E. M. Coltart,Romy Kerber,Damien Steer,Callum Wright,Francis Senyah,Sakoba Keita,Patrick Drury,Boubacar Diallo,Hilde De Clerck,Michel Van Herp,Armand Sprecher,Alexis Traoré,Mandiou Diakite,Mandy Kader Kondé,Lamine Koivogui,N’Faly Magassouba,Tatjana Avšič-Županc,Andreas Nitsche,Marc Strasser,Giuseppe Ippolito,Stephan Becker,Kilian Stoecker,Martin Gabriel,Hervé Raoul,Antonino Di Caro,Roman Wölfel,Pierre Formenty,Stephan Günther +131 more
TL;DR: Deep sequencing of 179 patient samples processed by the European Mobile Laboratory, the first diagnostics unit to be deployed to the epicentre of the outbreak in Guinea, reveals an epidemiological and evolutionary history of the epidemic from March 2014 to January 2015, providing an unprecedented window into the evolution of an ongoing viral haemorrhagic fever outbreak.
Evidence for SARS-CoV-2 Delta and Omicron co-infections and recombination
Alexandre Bolze,S. White,Tina Basler,Andrew Dei Rossi,Pavitra Roychoudhury,Alexander L. Greninger,Kathleen C. Hayashibara,D. R. Wyman,Eui Jun Kil,H. Dai,T. Cassens,K H Tsan,J. Nguyen,J. Ramirez,Stephanie Carter,Elizabeth T. Cirulli,Kelly M. Schiabor Barrett,Pedro Belda-Ferre,Nicole L. Washington,S. Jacobs,Efren Sandoval,Dirk Becker,J. T. Lu,Magnus Isaksson,W. Lee,Shengmei Luo +25 more
TL;DR: In this article , the presence and fraction of reads supporting mutations specific to either the Delta or Omicron variants of SARS-CoV-2 was analyzed and the authors identified 18 co-infections, one of which displayed evidence of a low Delta-Omicron recombinant virus population.
86
Concurrent human antibody andTH1 type T-cell responses elicited by a COVID-19 RNA vaccine
Ugur Sahin,Alexander Muik,Evelyna Derhovanessian,Isabel Vogler,Lena M. Kranz,Mathias Vormehr,Alina Baum,Kristen E. Pascal,Jasmin Quandt,Daniel Maurus,Sebastian Brachtendorf,Verena L Loerks,Julian Sikorski,Rolf Hilker,Dirk Becker,Ann-Kathrin Eller,Jan Gruetzner,Carsten Boesler,Corinna Rosenbaum,Marie-Cristine Kuehnle,Ulrich Luxemburger,Alexandra Kemmer-Brueck,David J. Langer,Martin Bexon,Stefanie Bolte,Katalin Karikó,Tania Palanche,Boris Fischer,Armin Schultz,Pei Yong Shi,Camila R. Fontes-Garfias,John L. Perez,Kena A. Swanson,Jakob Loschko,Ingrid L. Scully,Mark Cutler,Warren Kalina,Christos A. Kyratsous,David A. Cooper,Philip R. Dormitzer,Kathrin U. Jansen,Oezlem Tuereci +41 more
TL;DR: The robust RBD-specific antibody, T-cell and favourable cytokine responses induced by the BNT162b1 mRNA vaccine suggest multiple beneficial mechanisms with potential to protect against COVID-19.