8 Papers
8 Citations
Ding Tan is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Chemistry & Macrophage polarization. The author has an hindex of 5, co-authored 8 publications.
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Papers
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Xuankang Wang,Xin Li,Xiaoshuang Zuo,Zhuowen Liang,Ding Tan,Kun Li,Yangguang Ma,Penghui Li,Zhijie Zhu,Cheng Ju,Zhihao Zhang,Zhiwen Song,Huilin Quan,Jiawei Zhang,Xueyu Hu,Zhe Wang +15 more
TL;DR: In this article, the authors investigated whether photobiomodulation (PBM) can promote functional recovery by reducing neuroinflammation after spinal cord injury (SCI), but little is known about the underlying mechanism.
75
Attenuation of the inflammatory response and polarization of macrophages by photobiomodulation
Kun Li,Zhuowen Liang,Jiawei Zhang,Xiaoshuang Zuo,Jiakai Sun,Qiao Zheng,Jiwei Song,Ding Tan,Xueyu Hu,Zhe Wang +9 more
TL;DR: Results suggest that PBM can successfully modulate inflammation and polarization in classically activated BMDMs, providing a theoretical basis to support wider clinical application of PBM in the treatment of SCI.
28
Photobiomodulation Therapy Inhibit the Activation and Secretory of Astrocytes by Altering Macrophage Polarization
Jiakai Sun,Jiawei Zhang,Kun Li,Qiao Zheng,Jiwei Song,Zhuowen Liang,Ding Tan,Lin Qiao,Jianxin Zhang,Xueyu Hu,Zhe Wang +10 more
TL;DR: Results demonstrate that PBM may regulate the interaction between macrophages and astrocytes after spinal cord injury, which inhibited the formation of glial scar.
24
Photobiomodulation and diffusing optical fiber on spinal cord's impact on nerve cells from normal spinal cord tissue in piglets.
Xiaoshuang Zuo,Zhuowen Liang,Jiawei Zhang,Shuang Wang,Qiao Zheng,Yangguang Ma,Penghui Li,Ding Tan,Xueyu Hu,Zhe Wang +9 more
TL;DR: In this article, an implantable optical fiber that one can embed above the spinal cord lamina, and the light directly is cast onto the surface of spinal cord in a way that can dramatically improve energy use, but it remains to be seen whether near infrared light diffused by embedded optical fiber can have side effects on the surrounding nerve cells.
8
Photobiomodulation Inhibits the Activation of Neurotoxic Microglia and Astrocytes Through Inhibiting the Crosstalk of Lcn2/JAK2-STAT3 after Spinal Cord Injury in Rats
Xuankang Wang,Xin Li,Xiaoshuang Zuo,Zhuowen Liang,Zhe Wang,Ding Tan,Kun Li,Yangguang Ma,Penghui Li,Zhijie Zhu,Cheng Ju,Zhihao Zhang,Zhiwen Song,Huilin Quan,Jiawei Zhang,Xueyu Hu +15 more
- 07 May 2021
TL;DR: The crosstalk of Lcn2/JAK2-STAT3 is involved in the activation of neurotoxic microglia and astrocytes after SCI, and this process can be alleviated by PBM.