12 Papers
5 Citations
Die Hu is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Genome-wide association study & DNA damage. The author has an hindex of 8, co-authored 12 publications.
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Papers
Dose-Response Relationships of Polycyclic Aromatic Hydrocarbons Exposure and Oxidative Damage to DNA and Lipid in Coke Oven Workers
Dan Kuang,Wangzhen Zhang,Qifei Deng,Xiao Zhang,Kun Huang,Lei Guan,Die Hu,Tangchun Wu,Huan Guo +8 more
TL;DR: The findings demonstrate that urinary 1-hydroxypyrene is a useful biomarker for evaluating total PAHs exposure and assessing oxidative damage in coke oven workers and indicated that urinary ΣOH-PAHs and plasma BPDE-Alb adducts can result in significant dose-related increases in oxidative damage to DNA and lipids.
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Plasma microRNA expression and micronuclei frequency in workers exposed to polycyclic aromatic hydrocarbons
Qifei Deng,Suli Huang,Xiao Zhang,Wangzhen Zhang,Jing Feng,Tian Wang,Die Hu,Lei Guan,Jun Li,Xiayun Dai,Huaxin Deng,Xiaomin Zhang,Tangchun Wu +12 more
TL;DR: In this paper, the authors show that ubiquitous polycyclic aromatic hydrocarbons (PAHs) have been shown to alter gene expression patterns and elevate micronuclei (MN) frequency.
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Circulating MicroRNAs and the Occurrence of Acute Myocardial Infarction in Chinese Populations
Suli Huang,Mu Chen,Lu Li,Meian He,Die Hu,Xiaomin Zhang,Jun Li,Robert M. Tanguay,Jing Feng,Longxian Cheng,Hesong Zeng,Xiayun Dai,Qifei Deng,Frank B. Hu,Tangchun Wu +14 more
TL;DR: The plasma levels ofmiR-320b and miR-125b were significantly lower in patients with AMI when compared with controls, and these miRNAs may be involved in the pathogenesis of coronary heart disease.
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A Genome‐Wide Association Study for Serum Bilirubin Levels and Gene‐Environment Interaction in a Chinese Population
Xiayun Dai,Chen Wu,Yunfeng He,Lixuan Gui,Li Zhou,Li Zhou,Huan Guo,Jing Yuan,Binyao Yang,Jun Li,Qifei Deng,Suli Huang,Lei Guan,Die Hu,Jiang Zhu,Xinwen Min,Mingjian Lang,Dongfeng Li,Handong Yang,Frank B. Hu,Dongxin Lin,Tangchun Wu,Meian He +22 more
TL;DR: Single nucleotide polymorphism (SNP) rs2417940 had stronger effects on total bilirubin levels in nonsmokers than in smokers, suggesting that the effects of SLCO1B3 genotype on bilirUBin levels were partly dependent on smoking status.
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Polycyclic aromatic hydrocarbons-associated microRNAs and their interactions with the environment: influences on oxidative DNA damage and lipid peroxidation in coke oven workers.
Qifei Deng,Xiayun Dai,Huan Guo,Suli Huang,Dan Kuang,Jing Feng,Tian Wang,Wangzhen Zhang,Kun Huang,Die Hu,Huaxin Deng,Xiaomin Zhang,Tangchun Wu +12 more
TL;DR: The results suggested that miRNAs and their interactions with environmental factors might be novel mechanisms mediating the effects of PAHs exposure on oxidative DNA damage and lipid peroxidation.
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