Diana García-Moreno
University of Murcia
46 Papers
140 Citations
Diana García-Moreno is an academic researcher from University of Murcia. The author has contributed to research in topics: Biology & Zebrafish. The author has an hindex of 15, co-authored 34 publications. Previous affiliations of Diana García-Moreno include Carlos III Health Institute.
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Papers
Gasdermin E mediates pyroptotic cell death of neutrophils and macrophages in a zebrafish model of chronic skin inflammation.
Juan M. Lozano-Gil,Lola Rodríguez-Ruiz,Sylwia D. Tyrkalska,Diana García-Moreno,Ana B. Pérez-Oliva,Victoriano Mulero +5 more
TL;DR: In this article , the authors used the unique advantages of the zebrafish model to demonstrate that genetic inhibition of macrophage inflammasome resulted in increased number of Macrophages in larvae with skin inflammation without affecting erythrocyte and neutrophil counts.
Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness.
Manuel Bernabé-García,Elena Martínez-Balsalobre,Diana García-Moreno,Diana García-Moreno,Jesús García-Castillo,Beatriz Revilla-Nuin,Elena Blanco-Alcaina,Victoriano Mulero,Victoriano Mulero,Francisca Alcaraz-Pérez,María L. Cayuela +10 more
TL;DR: In this paper, the authors reported that TERT binds directly to the TCF binding elements (TBE) located upstream of the oncomiR miR500A, and induces its transcription.
Zebrafish Models to Study the Crosstalk between Inflammation and NADPH Oxidase-Derived Oxidative Stress in Melanoma
TL;DR: Models capable of studying the relevance of inflammation and oxidative stress in the early steps of melanocyte transformation are urgently needed, as they are expected to help recognize premetastatic lesions in patients by improving both early detection and the development of new therapies.
The zebrafish: A research model to understand the evolution of vertebrate immunity.
Diana García-Moreno,Sylwia D. Tyrkalska,Ana Valera-Pérez,Elena Gómez-Abenza,Ana B. Pérez-Oliva,Victoriano Mulero +5 more
TL;DR: The zebrafish has unique advantages for understanding the evolution of vertebrate immunity and to model human diseases, including to the identification of novel inflammasome components and to the mechanisms involved in its activation, assembly and clearance of intracellular bacteria.
Zebrafish Models to Study Inflammasome-Mediated Regulation of Hematopoiesis.
Lola Rodríguez-Ruiz,Juan M. Lozano-Gil,Christophe Lachaud,Pablo Mesa-del-Castillo,María L. Cayuela,Diana García-Moreno,Ana B. Pérez-Oliva,Victoriano Mulero +7 more
TL;DR: These are the zebrafish models that are currently available to study this unappreciated role of inflammasome-mediated regulation of hematopoiesis, and novel putative therapeutic strategies, for the treatment of hepatopoietic alterations associated with chronic inflammatory diseases in humans, are proposed.