Devorah Segal
Cornell University
20 Papers
119 Citations
Devorah Segal is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & White matter. The author has an hindex of 9, co-authored 17 publications. Previous affiliations of Devorah Segal include New York University & University of Medicine and Dentistry of New Jersey.
Chat about Author
Papers
Oligodendrocyte pathophysiology: a new view of schizophrenia
TL;DR: The MAG knockout mouse, missing a myelin-related gene linked to schizophrenia, may prove to be a useful animal model for the dysmyelination observed in the human disease.
91
Linking white and grey matter in schizophrenia: oligodendrocyte and neuron pathology in the prefrontal cortex
Malin Höistad,Devorah Segal,Nagahide Takahashi,Takeshi Sakurai,Joseph D. Buxbaum,Patrick R. Hof +5 more
TL;DR: Some recent morphological findings supporting possible causal involvement of white and grey matter abnormalities are presented, in the aim of determining the morphologic characteristics of the circuits whose alteration leads to the cortical dysfunction that possibly underlies the pathogenesis of schizophrenia.
Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia
Darius Ebrahimi-Fakhari,Julian Teinert,Julian Teinert,Robert Behne,Robert Behne,Miriam Wimmer,Angelica D'Amore,Kathrin Eberhardt,Barbara Brechmann,Marvin Ziegler,Dana M. Jensen,Premsai Nagabhyrava,Gregory Geisel,Erin Carmody,Uzma Shamshad,Kira A. Dies,Christopher J. Yuskaitis,Catherine L. Salussolia,Daniel Ebrahimi-Fakhari,Daniel Ebrahimi-Fakhari,Toni S. Pearson,Afshin Saffari,Andreas Ziegler,Stefan Kölker,Jens Volkmann,Antje Wiesener,David Bearden,Shenela Lakhani,Devorah Segal,Anaita Udwadia-Hegde,Andrea Martinuzzi,Jennifer Hirst,Seth Perlman,Yoshihisa Takiyama,Georgia Xiromerisiou,Katharina Vill,William O. Walker,Anju Shukla,Rachana Dubey Gupta,Niklas Dahl,Ayse Aksoy,Helene Verhelst,Mauricio R. Delgado,Radka Kremlikova Pourova,Abdelrahim Abdrabou Sadek,Nour Elkhateeb,Lubov Blumkin,Alejandro Brea-Fernández,David Dacruz-Álvarez,Thomas Smol,Jamal Ghoumid,Diego Miguel,Constanze Heine,Jan Ulrich Schlump,Hendrik Langen,Jonathan Baets,Saskia Bulk,Hossein Darvish,Somayeh Bakhtiari,Michael C. Kruer,Elizabeth Lim-Melia,Nur Aydinli,Yasemin Alanay,Omnia Fathy El-Rashidy,Sheela Nampoothiri,Chirag Patel,Christian Beetz,Peter O. Bauer,Grace Yoon,Mireille Guillot,Steven P. Miller,Thomas Bourinaris,Henry Houlden,Laura Robelin,Mathieu Anheim,Abdullah Alamri,Adel A. Mahmoud,Soroor Inaloo,Parham Habibzadeh,Mohammad Ali Faghihi,Mohammad Ali Faghihi,Anna Jansen,Stefanie Brock,Agathe Roubertie,Basil T. Darras,Pankaj B. Agrawal,Filippo M. Santorelli,Joseph G. Gleeson,Maha S. Zaki,Sarah I. Sheikh,James T. Bennett,Mustafa Sahin +91 more
TL;DR: It is found that the presence of epilepsy, which manifested before the age of 3 years in the majority of patients, was associated with worse motor outcomes and the relationship between disease severity as measured by several rating scales and disease duration.
Adaptor protein complex 4 deficiency: a paradigm of childhood-onset hereditary spastic paraplegia caused by defective protein trafficking
Robert Behne,Julian Teinert,Julian Teinert,Miriam Wimmer,Angelica D'Amore,Alexandra K Davies,Alexandra K Davies,Joseph M. Scarrott,Kathrin Eberhardt,Barbara Brechmann,Ivy Pin-Fang Chen,Elizabeth D. Buttermore,Lee Barrett,Sean Dwyer,Teresa Chen,Jennifer Hirst,Antje Wiesener,Devorah Segal,Andrea Martinuzzi,Sofia T. Duarte,James T. Bennett,Thomas Bourinaris,Henry Houlden,Agathe Roubertie,Filippo M. Santorelli,Margaret S. Robinson,Mimoun Azzouz,Jonathan O. Lipton,Jonathan O. Lipton,Georg H. H. Borner,Mustafa Sahin,Darius Ebrahimi-Fakhari +31 more
TL;DR: Examining the downstream effects of ATG9A mislocalization, it is found that autophagic flux was intact in patient-derived fibroblasts both under nutrient-rich conditions and when autophagy is stimulated, suggesting a neuron-specific alteration in autophagosome turnover.
59
Spatial distribution and density of oligodendrocytes in the cingulum bundle are unaltered in schizophrenia
TL;DR: No significant differences in the oligodendrocyte distribution or density in the cingulum bundle between the two groups are found, in contrast to earlier data from the prefrontal subcortical white matter.
46