Devin McAvoy
18 Papers
Devin McAvoy is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 5 publications.
Chat about Author
Papers
GPRC5D-Targeted CAR T Cells for Myeloma.
Sham Mailankody,Sean M. Devlin,Jonathan Landa,Karthik Nath,Claudia Diamonte,Elizabeth J. Carstens,Douglas Russo,Romany Auclair,Lisa Fitzgerald,Briana R. Cadzin,Xiu-Li Wang,Devanjan Sikder,Brigitte Senechal,Vladimir P. Bermudez,Terence J. Purdon,Kinga K. Hosszu,Devin McAvoy,Tasmin Farzana,Elena Mead,Jessica A. Wilcox,Bianca Santomasso,Gunjan L. Shah,Urvi A Shah,Neha Korde,Alexander M. Lesokhin,Carlyn Rose C. Tan,Malin Hultcrantz,Hani Hassoun,Mikhail Roshal,Filiz Sen,Ahmet Dogan,Ola Landgren,Sergio Giralt,Jae H. Park,Saad Usmani,Isabelle Riviere,Renier J. Brentjens,Eric L. Smith +37 more
TL;DR: The results of this phase 1 dose-escalation study confirm that GPRC5D is an active immunotherapeutic target in multiple myeloma.
47
Sustained Minimal Residual Disease Negativity in Multiple Myeloma is Associated with Stool Butyrate and Healthier Plant-Based Diets
Urvi A Shah,Kylee H Maclachlan,Andriy Derkach,M Salcedo,Kelly A. Barnett,Julia Caple,Jenna Blaslov,Linh Tran,Amanda Ciardiello,M. Burge,Tala Shekarkhand,Peter A. Adintori,Justin R. Cross,Matthew J. Pianko,Kinga K. Hosszu,Devin McAvoy,Sham Mailankody,Neha Korde,Malin Hultcrantz,Hani Hassoun,Carlyn Rose C. Tan,Sydney X. Lu,Dhwani Patel,Benjamin Diamond,Gunjan L. Shah,Michael Scordo,Oscar B Lahoud,David J. Chung,Heather Landau,Saad Usmani,Sergio Giralt,Ying Taur,C. Ola Landgren,Gladys Block,Torin Block,Jonathan U. Peled,Marcel R.M. van den Brink,Alexander M. Lesokhin +37 more
TL;DR: This is the first study to demonstrate an association between a plant-based dietary pattern, stool butyrate production and sustained MRD-negativity in MM; providing rationale to evaluate a prospective dietary intervention.
18
CD8 effector T cells enhance response in BCMA-exposed and -naïve multiple myeloma.
Ross Firestone,Devin McAvoy,Tala Shekarkhand,Edith Serrano,Issam Hamadeh,Alice Wang,Menglei Zhu,Dhwani Patel,C. Tan,Malin Hultcrantz,Sham Mailankody,Hani Hassoun,Urvi A Shah,Neha Korde,Kylee H Maclachlan,Heather Landau,Michael Scordo,Gunjan L. Shah,Oscar B Lahoud,Sergio A. Giralt,Kazunori Murata,Kinga K. Hosszu,David J. Chung,Alexander M. Lesokhin,Saad Usmani +24 more
TL;DR: Teclistamab is effective in real-world patients with R/RMM, including those with prior anti-BCMA therapy exposure, albeit with slightly poorer progression-free survival, albeit with slightly poorer progression-free survival.
14
A Pilot Plant Based Dietary Intervention in MGUS and SMM Patients with Elevated BMI Is Feasible and Associated with Improvements in Metabolic and Microbiome Biomarkers of Progression
Urvi A Shah,Andriy Derkach,Francesca Castro,Aishwarya Anuraj,Jenna Blaslov,Linh A. Tran,Peter A. Adintori,M. Burge,Sharon Funkhouser,Kinga K. Hosszu,Justin R. Cross,Michael Pollak,Devin McAvoy,D. M. Nemirovsky,Kylee H Maclachlan,Sham Mailankody,Neha Korde,Carlyn Rose C. Tan,Malin Hultcrantz,Dhwani Patel,Hani Hassoun,Gunjan L. Shah,Michael Scordo,Oscar B Lahoud,David J. Chung,Marius E. Mayerhoefer,Jonathan U. Peled,Heather Landau,Anita D'Souza,Ola Landgren,Sergio Giralt,Neil M. Iyengar,Saad Usmani,Marcel R.M. van den Brink,Alexander M. Lesokhin +34 more
TL;DR: In this paper , a pilot dietary intervention study (NUTRIVENTION) of a whole food plant-based diets (WFPBDs) in MGUS/SMM patients with BMI ≥ 25 was conducted.
6
A Whole Foods Plant-Based Weight Loss Intervention Improves Quality of Life, Metabolic, Microbiome and Immune Profile in MGUS/SMM As Well As Progression Trajectory in a Subset - the Nutrivention Trial
Urvi A Shah,Francesca Castro,Andriy Derkach,Teng Fei,Kinga K. Hosszu,Devin McAvoy,Susan DeWolf,Justin Cross,Ana Gradissimo,Alexis Nwankwo,Aishwarya Anuraj,M. Burge,Blaslov Jenna,Elizabeth Raynor,Jenna Wosleger,Peter A. Adintori,Michael Pollak,Jenny Paredes Sanchez,Thomas Atkinson,Kylee H Maclachlan,Sham Mailankody,Neha Korde,C. Tan,Malin Hultcrantz,Hani Hassoun,Jonathan U. Peled,Gunjan L. Shah,Michael Scordo,Oscar B Lahoud,David Chung,Heather Landau,Anita D'Souza,O. Landgren,Sergio A. Giralt,Neil M. Iyengar,Saad Usmani,Alexander M. Lesokhin,Marcel R.M. van den Brink +37 more
TL;DR: Prelim results at 12w suggest a measurable, albeit not significant change in immune subsets such as an increase in monocytes, regulatory T cells, and a decrease in dendritic cells, trends previously associated with anti-inflammatory diets, as well as increase in butyrate.
3