Devin M. Christopher
University of Pennsylvania
7 Papers
Devin M. Christopher is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of Devin M. Christopher include University of New Mexico.
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Papers
Fragile X Proteins FMRP and FXR2P Control Synaptic GluA1 Expression and Neuronal Maturation via Distinct Mechanisms.
Weixiang Guo,Weixiang Guo,Eric D. Polich,Juan Su,Yu Gao,Devin M. Christopher,Andrea M. Allan,Min Wang,Feifei Wang,Guangfu Wang,Xinyu Zhao +10 more
TL;DR: It is discovered thatFXR2P (also known as FXR2) is important for neuronal dendritic development and a regulatory mechanism of GluA1 is uncovered, which reveals a functional convergence between fragile X proteins in neuronal development.
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Collection of triatomines from sylvatic habitats by a Trypanosoma cruzi-infected scent detection dog in Texas, USA
Devin M. Christopher,Rachel Curtis-Robles,Gabriel L. Hamer,Justin R Bejcek,Ashley B. Saunders,Walter Roachell,Thomas L Cropper,Sarah A. Hamer +7 more
TL;DR: Ziza, a 3-year-old German Shorthaired Pointer previously naturally infected with T. cruzi, was trained to detect triatomines in sylvatic habitats as discussed by the authors .
Collection of triatomines from sylvatic habitats by a Chagas-positive, trained scent-detection canine in Texas, USA
Devin M. Christopher,Rachel Curtis-Robles,Gabriel L. Hamer,Justin R Bejcek,Ashley B. Saunders,Walter Roachell,Thomas L Cropper,Sarah A. Hamer +7 more
TL;DR: A trained scent detection dog enhanced triatomine detections in sylvatic habitats and offered opportunities for continued exploration of novel vector control methods to block the transmission of T. cruzi to humans and domestic animals.
Patent
Compositions comprising a lecithin cholesterol acyltransferase variant and uses thereof
Daniel J. Rader,Devin M. Christopher,Anna P. Tretiakova +2 more
- 24 Jul 2017
TL;DR: A synthetic or recombinant human lecithin cholesterol acyltransferase (LCAT) variant is provided in this paper which comprises an LCAT enzyme having a substitution at position 114 based on the residue numbering of wild-type (WT) human LCAT.
Lessons Learned from the Clinical Development and Market Authorization of Glybera
Laura Bryant,Devin M. Christopher,April R. Giles,Christian Hinderer,Jesse L. Rodriguez,Jenessa B. Smith,Elizabeth A. Traxler,Josh Tycko,Adam P. Wojno,James M. Wilson +9 more
TL;DR: Key data from human and animal studies are reviewed with an emphasis on issues that will be critical to other gene therapy products.