Dennis S. Charney
Icahn School of Medicine at Mount Sinai
822 Papers
11.8K Citations
Dennis S. Charney is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Anxiety & Medicine. The author has an hindex of 179, co-authored 802 publications. Previous affiliations of Dennis S. Charney include Mount Sinai Hospital & Veterans Health Administration.
Chat about Author
Papers
Intravenous diazepam fails to change growth hormone and cortisol secretion in humans
TL;DR: A placebo-controlled investigation determined plasma GH and cortisol levels after intravenous administration of diazepam (0.15 mg/kg) to 10 healthy volunteers and found neither GH nor cortisol secretion changed significantly afterdiazepam infusion.
30
Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: Support for serotonin-2 receptor modulation of schizophrenia symptoms
Walid M. Abi-Saab,John Seibyl,Cyril D'Souza,Laurence P. Karper,Ralitza Gueorgueva,Anissa Abi-Dargham,Ma-Li Wong,Sachin Rajhans,Joseph P. Erdos,George R. Heninger,Dennis S. Charney,John H. Krystal +11 more
TL;DR: Data support a contribution of 5- HT2 receptor stimulation to symptom exacerbation in schizophrenic patients and a role for 5-HT2 receptor antagonism in the prevention of this effect.
29
Neuroimaging correlates and predictors of response to repeated-dose intravenous ketamine in PTSD: preliminary evidence.
Agnes Norbury,Sarah B Rutter,Abigail B Collins,Sara Costi,Manish K. Jha,Sarah R. Horn,Marin Kautz,Morgan Corniquel,Katherine A. Collins,Katherine A. Collins,Andrew M Glasgow,Jess W. Brallier,Lisa M. Shin,Lisa M. Shin,Dennis S. Charney,James W. Murrough,Adriana Feder +16 more
TL;DR: In this paper, the authors explore the neural correlates of ketamine-related changes in PTSD symptoms, using a rich battery of functional imaging data (two emotion-processing tasks and one task-free scan), collected from a subset of participants of a randomized clinical trial of repeated-dose intravenous ketamine vs midazolam (total N = 21).
29
Reserpine augmentation of desipramine in refractory depression: clinical and neurobiological effects.
TL;DR: Despite robust effects on central monoamine metabolism, reserpine augmentation appears insufficiently effective for routine use in managing refractory depression.
29
The MCP-4/MCP-1 ratio in plasma is a candidate circadian biomarker for chronic post-traumatic stress disorder.
Clifton L. Dalgard,Ofer Eidelman,Catherine Jozwik,Cara H. Olsen,Meera Srivastava,Roopa Biswas,Y Eudy,Stephen W. Rothwell,Gregory P. Mueller,Peixiong Yuan,Wayne C. Drevets,Husseini K. Manji,M Vythlingam,Dennis S. Charney,Alexander Neumeister,Robert J. Ursano,David M. Jacobowitz,Harvey B. Pollard,O Bonne +18 more
TL;DR: In plasma, but not CSF, the bivariate MCP4 (CCL13)/ MCP1(CCL2) ratio is ca.