Dennis S. Charney
Icahn School of Medicine at Mount Sinai
822 Papers
11.8K Citations
Dennis S. Charney is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Anxiety & Medicine. The author has an hindex of 179, co-authored 802 publications. Previous affiliations of Dennis S. Charney include Mount Sinai Hospital & Veterans Health Administration.
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Papers
MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress Disorder
J. Douglas Bremner,Meena Vythilingam,Eric Vermetten,Steven M. Southwick,Thomas H. McGlashan,Ahsan Nazeer,Sarfraz Khan,L. Viola Vaccarino,Robert Soufer,Pradeep K. Garg,Chin K. Ng,Lawrence H. Staib,James S. Duncan,Dennis S. Charney +13 more
TL;DR: The results of this study are consistent with deficits in hippocampal function and structure in abuse-related PTSD.
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Elevated CSF Corticotropin-Releasing Factor Concentrations in Posttraumatic Stress Disorder
J. Douglas Bremner,Julio Licinio,Adam Darnell,John H. Krystal,Michael J. Owens,Steven M. Southwick,Charles B. Nemeroff,Dennis S. Charney +7 more
TL;DR: Higher CSFCRF concentrations in patients with PTSD may reflect alterations in stress-related neurotransmitter systems, and the higher CSF CRF concentrations may play a role in disturbances of arousal in Patients with PTSD.
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Defining Clinical Phenotypes of Juvenile Mania
TL;DR: The presence of distinct episodes and hallmark symptoms can be used to differentiate clinical phenotypes of juvenile mania and the utility and validity of this system can be tested in subsequent research.
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Neural Correlates of Memories of Childhood Sexual Abuse in Women With and Without Posttraumatic Stress Disorder
J. D. Bremner,Meena Narayan,Lawrence H. Staib,Steven M. Southwick,Thomas H. McGlashan,Dennis S. Charney +5 more
TL;DR: These findings implicate dysfunction of medial prefrontal cortex (subcallosal gyrus and anterior cingulate), hippocampus, and visual association cortex in pathological memories of childhood abuse in women with PTSD.
717
Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression
Marije aan het Rot,Katherine A. Collins,James W. Murrough,Andrew M. Perez,David Reich,Dennis S. Charney,Sanjay J. Mathew +6 more
TL;DR: These pilot findings suggest feasibility of repeated-dose IV ketamine for the acute treatment of TRD and change from baseline in the Montgomery-Asberg Depression Rating Scale score.
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