Dennis S. Charney
Icahn School of Medicine at Mount Sinai
822 Papers
11.8K Citations
Dennis S. Charney is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Anxiety & Medicine. The author has an hindex of 179, co-authored 802 publications. Previous affiliations of Dennis S. Charney include Mount Sinai Hospital & Veterans Health Administration.
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Papers
•Journal Article
Compartmental modeling of iodine-123-iodobenzofuran binding to dopamine D2 receptors in healthy subjects.
Marc Laruelle,van Dyck C,Anissa Abi-Dargham,Yolanda Zea-Ponce,Sami S. Zoghbi,Dennis S. Charney,R. M. Baldwin,Paul B. Hoffer,Hank F. Kung,Robert B. Innis +9 more
TL;DR: Iodine-131-IBF is a suitable ligand for quantitative studies of D2 receptor density with SPECT in humans and demonstrates reversibility, with peak basal ganglia uptake at 50 +/- 25 min.
97
Biased emotional attention in post-traumatic stress disorder: a help as well as a hindrance?
Meena Vythilingam,Karina Blair,Daniel McCaffrey,Matthew Scaramozza,Matthew F. Jones,Marina Nakic,K. Mondillo,Kayleen Hadd,Omer Bonne,Derek G.V. Mitchell,Daniel S. Pine,Dennis S. Charney,Robert James Blair +12 more
TL;DR: These findings document that hyper-responsiveness to threat but not to positive stimuli is specific for patients with PTSD.
96
Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans.
Alexander Neumeister,Dennis S. Charney,Inna Belfer,Marilla Geraci,Courtney Holmes,Yehonatan Sharabi,Tanya N. Alim,Omer Bonne,David A. Luckenbaugh,Husseini K. Manji,David Goldman,David S. Goldstein +11 more
TL;DR: In healthy people, &agr;2CDel322–325 polymorphism is associated with increased sympathetic nervous and adrenomedullary hormonal activities, both during supine rest and during pharmacologically evoked catecholamine release.
95
Evidence of acoustic startle hyperreflexia in recently detoxified early onset male alcoholics: modulation by yohimbine and m-Chlorophenylpiperazine (mCPP)
John H. Krystal,Elizabeth Webb,Christian Grillon,Ned L. Cooney,Lisa Casal,C. A. Morgan Iii.,Steven M. Southwick,Michael Davis,Dennis S. Charney +8 more
TL;DR: These data replicate and extend previous reports indicating that yohimbine facilitates the acoustic startle response in humans and further implicate the number of episodes of ethanol withdrawal as a factor influencing subsequent neurobiological responsivity in chronic alcoholic patients.
95
Trauma-Related Symptoms in Veterans of Operation Desert Storm: A Preliminary Report
Steven M. Southwick,Andrew S. Morgan,Linda M. Nagy,Douglas Bremner,Andreas L. Nicolaou,David Read Johnson,Robert A. Rosenheck,Dennis S. Charney +7 more
TL;DR: Preliminary findings suggest that a high percentage of Desert Storm veterans experienced some trauma-related symptoms after returning to the United States.
95