Denis Querleu
McGill University
6 Papers
26 Citations
Denis Querleu is an academic researcher from McGill University. The author has contributed to research in topics: Ovarian cancer & Copy-number variation. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Denis Querleu include Cornell University & Paul Sabatier University.
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Papers
Gene expression analysis of matched ovarian primary tumors and peritoneal metastasis
Joel A. Malek,Alejandra Martinez,Eliane Mery,Gwenael Ferron,Ruby Yun-Ju Huang,Christophe M. Raynaud,Eva Jouve,Jean Paul Thiery,Denis Querleu,Arash Rafii +9 more
TL;DR: It is shown that gene expression profiles in peritoneal metastasis are significantly different than their matched primary tumor and these changes are affected by underlying copy number variation differences among other causes.
Prise en charge chirurgicale des ganglions dans le cancer de l’endomètre au stade I
TL;DR: In 2010, l’institut national de lutte contre le cancer (INCa) published a set of recommandations for the pratique clinique (RPC) as discussed by the authors.
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Utilisation de la voie laparoscopique extra-péritonéale pour la réalisation des lymphadenectomies aortiques chez des patientes obèses Extraperitoneal laparoscopic para-aortic lymph nodes dissection in obese patients
G. Ferron,A Martinez,Mathieu Poilblanc,Denis Querleu +3 more
- 01 Jan 2013
TL;DR: Gynecologic oncologists must master aortic lymphadenectomies in order to treat obese patients and respect guidelines in high risk endometrial cancer.
Tumor associated mesenchymal stem cells protects ovarian cancer cells from hyperthermia through CXCL12.
Raphael Lis,Cyril Touboul,Cyril Touboul,Pejman Mirshahi,Fadoua Ali,Sharon Mathew,Daniel J. Nolan,Mahtab Maleki,Salma A. Abdalla,Christophe M. Raynaud,Denis Querleu,Eman K. Al-Azwani,Joel A. Malek,Massoud Mirshahi,Arash Rafii +14 more
TL;DR: It is demonstrated that hyperthermia does not challenge survival of TAMC or bone marrow derived MSC (BM‐MSC) and co‐cultured with OCC induced thermotolerance in a CXCL12 dependant manner, and Targeting the interaction between stromal and cancer cells through CX CL12 inhibition might restore hyperThermia sensitivity in ovarian cancers, and thus improve HIPEC efficiency.
Copy number variation analysis of matched ovarian primary tumors and peritoneal metastasis.
Joel A. Malek,Eliane Mery,Yasmin A. Mahmoud,Eman K. Al-Azwani,Laurence Roger,Ruby Yun-Ju Huang,Eva Jouve,Raphael Lis,Jean Paul Thiery,Denis Querleu,Arash Rafii +10 more
TL;DR: Evidence is provided that ovarian tumors have specific copy number variation differences in many of these genes including the JAK/STAT and cytokine signaling pathways and it is shown that these copy number variations clearly differentially affect specific pathways.