Denis L. Bourke
Johns Hopkins University
9 Papers
162 Citations
Denis L. Bourke is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Local anesthetic & Medicine. The author has an hindex of 7, co-authored 9 publications.
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Papers
An interaction between aspirin and valproate: the relevance of plasma protein displacement drug-drug interactions.
TL;DR: Despite the ubiquity and severity of drug-drug interactions, this problem is one of the most poorly recognized and poorly understood issues within clinical medicine (1, 2). The impact of drugdrug interactions on patient safety is finally being elucidated, and the magnitude of the problem is vast as mentioned in this paper.
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Improved postoperative analgesia with morphine added to axillary block solution.
TL;DR: The addition of morphine 0.1 mg/kg to the local anesthetic axillary block solution provided improved postoperative analgesia without an increased frequency of side effects or major complications.
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Time course of sympathetic blockade during epidural anesthesia: laser Doppler flowmetry studies of regional skin perfusion.
TL;DR: It is confirmed that sympathetic block precedes sensory block in sacral dermatomes after epidural anesthesia, and perfusion and IGVR changes are sensitive measures of sympathetic blockade and may predict successful epidural catheter placement.
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Epidural opioids during laminectomy surgery for postoperative pain.
Denis L. Bourke,Edward Spatz,Edward Spatz,Ronald Motara,Ronald Motara,Joe I. Ordia,Joe I. Ordia,James Reed,James Reed,James M. Hlavacek,James M. Hlavacek +10 more
TL;DR: Morphine 3 mg applied topically to the dura at the end of laminectomy surgery is a simple, safe, and effective way of providing improved postoperative analgesia.
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Capacity to give surgical consent does not imply capacity to give anesthesia consent: implications for anesthesiologists.
TL;DR: The cases reported in this article show that capacity for surgical consent may be inadequate for consent to anesthesia because anesthesia involves more abstract concepts requiring a higher cognitive state than surgery, thus requiring aHigher state of cognitive capacity for understanding.
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