Dejun Gong
Second Military Medical University
35 Papers
251 Citations
Dejun Gong is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Mesenchymal stem cell & Cell growth. The author has an hindex of 14, co-authored 33 publications.
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Papers
MicroRNA-203 inhibits cell proliferation by repressing ΔNp63 expression in human esophageal squamous cell carcinoma
TL;DR: MiR-203 could down-regulate endogenous ΔNp63 expression at the posttranscriptional level and be used as a therapeutic agent for human ESCC through Δnp63-mediated signal pathway.
Therapeutic potential of angiogenin modified mesenchymal stem cells: angiogenin improves mesenchymal stem cells survival under hypoxia and enhances vasculogenesis in myocardial infarction.
TL;DR: Angiogenin modified MSCs enhanced the tolerance of engrafted MSC’s to hypoxia injury in vitro and improved their viability in infracted hearts, thus helping preserve the LV contractile function and attenuate LV remodeling through vasculogenesis.
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Efficient decellularization for bovine pericardium with extracellular matrix preservation and good biocompatibility.
TL;DR: The results suggested that the FTS protocol showed optimal decellularization results with better extracellular matrix preservation and good biocompatibility, and may be a suitable protocol for producing a suitable scaffold for heart tissue engineering.
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Transplantation of angiogenin-overexpressing mesenchymal stem cells synergistically augments cardiac function in a porcine model of chronic ischemia
Shengdong Huang,Fanglin Lu,Xun-Yu Xu,Xiao-hong Liu,Xian-Xian Zhao,Bao-Zhen Zhao,Li Wang,Dejun Gong,Yang Yuan,Zhi-yun Xu +9 more
TL;DR: Transplantation of autologous mesenchymal stem cells transfected with the angiogenin gene revealed a synergistic effect on the improvement of heart perfusion and function after ameroid occlusion.
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Tumor Cells Positive and Negative for the Common Cancer Stem Cell Markers Are Capable of Initiating Tumor Growth and Generating Both Progenies
Shengdong Huang,Yang Yuan,Hao Tang,Liu Xiaohong,Chuan-Gang Fu,He-Zhong Cheng,Jian-Wei Bi,Yongwei Yu,Dejun Gong,Wei Zhang,Jie Chen,Zhiyun Xu +11 more
TL;DR: It is demonstrated that tumorigenic cells cannot be distinguished by common CSC markers alone and it is proposed that cautions should be taken when using these markers independently to identify cancer stem cells due to the phenotypic plasticity of tumor cells.