Deepak Jain
Tengion
47 Papers
270 Citations
Deepak Jain is an academic researcher from Tengion. The author has contributed to research in topics: Regeneration (biology) & Kidney disease. The author has an hindex of 16, co-authored 42 publications. Previous affiliations of Deepak Jain include McGill University & University of Manitoba.
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Papers
Functional Evaluation of Primary Renal Cell/Biomaterial Neo-Kidney Augment Prototypes for Renal Tissue Engineering:
Joydeep Basu,Christopher W. Genheimer,Elias A. Rivera,Richard G. Payne,Kim L. Mihalko,Kelly I. Guthrie,Andrew T. Bruce,Neil Robbins,Darell W. McCoy,Namrata Sangha,Roger M. Ilagan,Toyin Knight,Thomas Spencer,Belinda J. Wagner,Manuel J. Jayo,Deepak Jain,John W. Ludlow,Craig Halberstadt +17 more
TL;DR: In vivo delivery of cell-seeded NKA constructs to healthy rodent renal parenchyma elicited neokidney tissue formation at 1 week postimplantation and the effect of conditioned media on TGF-β signaling pathways related to tubulo-interstitial fibrosis associated with CKD progression was evaluated.
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Patent
Scaffolds for organ reconstruction and augmentation
Timothy A. Bertram,Andrew T. Bruce,Deepak Jain,Manuel J. Jayo,John W. Ludlow,Darell W. McCoy,Richard G. Payne,Namrata Sangha +7 more
- 12 Feb 2007
TL;DR: In this paper, synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation, or replacement of organs or tissue structures in a patient in need of such treatment.
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Construction of a tubular scaffold that mimics J-shaped stress/strain mechanics using an innovative electrospinning technique.
Harry Scott Rapoport,Jeff Fish,Joydeep Basu,Jonathon Campbell,Christopher W. Genheimer,Richard G. Payne,Deepak Jain +6 more
TL;DR: An innovative electrospinning technique has been utilized to form tubular scaffold composites with structural features reminiscent of the corrugated laminae seen in blood vessels with the ability to match complex stress-strain behaviors in soft tissues with a high degree of fidelity.
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Pitx1 directly modulates the core limb development program to implement hindlimb identity.
TL;DR: A small set of limb type-restricted genes among the broadly conserved Pitx1 gene regulatory network, including components of the chondrogenic program, establishes hindlimb identity in mouse and supports a model in which multifactorial actions of a limited number of HL regulators redirect the generic limb development program in order to generate the unique structural features of the limb.
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Patent
Cell scaffold constructs
John W. Ludlow,Manuel J. Jayo,Joydeep Basu,Timothy A. Bertram,Christopher W. Genheimer,Kelly I. Guthrie,Roger M. Ilagan,Deepak Jain,Oluwatoyin A. Knight,Richard G. Payne,Sarah F. Quinlan,H. Scott Rapoport,Namrata Sangha +12 more
- 04 Nov 2009
TL;DR: In this article, the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
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