Deepa Subramanyam
Savitribai Phule Pune University
14 Papers
8 Citations
Deepa Subramanyam is an academic researcher from Savitribai Phule Pune University. The author has contributed to research in topics: Embryonic stem cell & Biology. The author has an hindex of 6, co-authored 14 publications.
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Papers
A MicroRNA/Ubiquitin Ligase Feedback Loop Regulates Slug-Mediated Invasion in Breast Cancer.
Rajesh Kumar Manne,Yashika Agrawal,Anil Bargale,Asha Patel,Debasish Paul,Neha Anilkumar Gupta,Srikanth Rapole,Vasudevan Seshadri,Deepa Subramanyam,Praveenkumar Shetty,Manas Kumar Santra +10 more
TL;DR: The results establish the presence of interplay between microRNAs and the ubiquitination machinery, which together regulate cancer cell invasion and establishes a positive feedback loop to maintain an invasive phenotype.
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Shaping Cell Fate: Influence of Topographical Substratum Properties on Embryonic Stem Cells.
Sarita Kumari,Steven Vermeulen,Ben van der Veer,Aurélie Carlier,Jan de Boer,Deepa Subramanyam +5 more
TL;DR: The role of mechanical properties during embryogenesis is reviewed and the effect of engineered microtopographies on ESC pluripotency is discussed and the underlying molecular mechanisms that regulate the behavior of embryonic stem cells are discussed.
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Stress - (Self) Eating: Epigenetic Regulation of Autophagy in Response to Psychological Stress
Deepika Puri,Deepa Subramanyam +1 more
TL;DR: The systematic study of these regulatory mechanisms will provide a novel therapeutic strategy, based on the use epigenetic regulators of autophagy to enhance neurogenesis and potentially alleviate stress‐related behavioral disorders.
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Dual repression of endocytic players by ESCC microRNAs and the Polycomb complex regulates mouse embryonic stem cell pluripotency
TL;DR: It is proposed that endocytosis is critical for cell fate choice, and dual repression may function to tightly regulate levels of endocytic genes.
Pluripotency of embryonic stem cells lacking clathrin-mediated endocytosis cannot be rescued by restoring cellular stiffness
Ridim D. Mote,Ridim D. Mote,Jyoti Yadav,Surya Bansi Singh,Mahak Tiwari,Shinde Laxmikant,Shivprasad Patil,Deepa Subramanyam +7 more
TL;DR: Using atomic force microscopy (AFM), it is demonstrated that mESCs lacking Cltc display higher Young's modulus, indicative of greater cellular stiffness, compared with WT m ESCs, which indicates that the presence of active CME is essential for the pluripotency of embryonic stem cells.
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