Dean Kracko
Lovelace Respiratory Research Institute
23 Papers
88 Citations
Dean Kracko is an academic researcher from Lovelace Respiratory Research Institute. The author has contributed to research in topics: Chemistry & Inhalation exposure. The author has an hindex of 12, co-authored 23 publications.
Chat about Author
Papers
Formation, Accumulation, and Hydrolysis of Endogenous and Exogenous Formaldehyde-Induced DNA Damage.
Rui Yu,Yongquan Lai,Hadley J. Hartwell,Benjamin C. Moeller,Melanie Doyle-Eisele,Dean Kracko,Wanda Bodnar,Thomas B. Starr,James A. Swenberg +8 more
TL;DR: N(2)-HOMe-dG was shown to be an excellent biomarker for direct adduction of formaldehyde to DNA and the hydrolysis of DPCs and support a data-driven need for reflection on whether risks have been overestimated for inhaled formaldehyde.
80
Chronic Self-Administration of Nicotine in Rats Impairs T Cell Responsiveness
TL;DR: The results suggest that chronic nicotine self-administration suppresses T cell responsiveness, and this suppression may result from an impaired TCR-mediated signaling that stems from the depletion of IP(3)-sensitive intracellular Ca(2+) stores.
35
•Journal Article
Medical nebulizer performance: effects of cascade impactor temperature.
TL;DR: The results provide important information for the use of a cascade impactor to measure the particle-size distribution of nebulizer aerosols.
32
Dosimetry of N6-formyllysine adducts following [ 13C2H2]-formaldehyde exposures in rats
Bahar Edrissi,Koli Taghizadeh,Benjamin C. Moeller,Dean Kracko,Melanie Doyle-Eisele,James A. Swenberg,Peter C. Dedon,Peter C. Dedon,Peter C. Dedon +8 more
TL;DR: In this paper, the authors quantified endogenous and exogenous N6-formyllysine in the nasal epithelium of rats exposed by inhalation to 0.13C2H2]-formaldehyde using liquid chromatography-coupled tandem mass spectrometry.
31
Inhalation Exposure Systems for the Development of Rodent Models of Sulfur Mustard-Induced Pulmonary Injury
Waylon Weber,Dean Kracko,Mericka R. Lehman,Clinton M. Irvin,Lee F. Blair,Richard K. White,Janet M. Benson,Gary R. Grotendorst,Yung-Sung Cheng,Jacob D. McDonald +9 more
TL;DR: The present manuscript details the techniques used to develop SM laboratory exposure systems for the development of animal models of pulmonary injury, critical for evaluating SM injury and developing therapeutics against that injury.
31