de Bart G. Grooth
University of Twente
5 Papers
261 Citations
de Bart G. Grooth is an academic researcher from University of Twente. The author has contributed to research in topics: Cytotoxic T cell & Actin. The author has an hindex of 5, co-authored 5 publications.
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Papers
Viscoelasticity of living cells allows high resolution imaging by tapping mode atomic force microscopy.
TL;DR: A new mode of operation is described in which the standard V-shaped silicon nitride cantilever is oscillated under liquid and damped by the interaction between AFM tip and sample surface, making it possible to study physiological processes, such as cell growth, with a minimal level of perturbation and high spatial resolution.
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White blood cell differentiation using a solid state flow cytometer
TL;DR: A flow cytometer using a solid state light source and detector, which was used to detect the weak scattered light in the orthogonal direction, yields similar results as a standard flow cytometers set-up using a helium-neon laser and photomultipliers.
Occurrence and a possible mechanism of penetration of natural killer cells into k562 target cells during the cytotoxic interaction
Katarina Radosevic,van Anne Marie T. Leeuwen,Ine M.J. Segers-Nolten,Carl G. Figdor,de Bart G. Grooth,Jan Greve +5 more
TL;DR: The study demonstrates that in-conjugation represents a significant fraction of the cytotoxic interaction and indicates that it may be a consequence of an actin polymerization and endonuclease activity dependent part of a cytot toxic mechanism.
Changes in actin organization during the cytotoxic process
Katarina Radosevic,van Anne Marie T. Leeuwen,Ine M.J. Segers-Nolten,Carl G. Figdor,de Bart G. Grooth,Jan Greve +5 more
TL;DR: Changes in organization of F-actin during the cytotoxic process between NK and K562 cells have been observed and studied using confocal laser scanning microscopy and quantitative fluorescence microscopy.
Cytotoxic lymphocytes in B-cell chronic lymphocytic leukemia A flow cytometric study of peripheral blood, lymph nodes and bone marrow
TL;DR: In this paper, the occurrence of cytotoxic lymphocyte subpopulations (i.e., CD 16+, CD 57+, CD 16+ and CD 8+) was studied in the peripheral blood of 18 B-cell chronic lymphocytic leukemia (B-CLL) patients.