Dayami Lopez
University of South Florida
30 Papers
247 Citations
Dayami Lopez is an academic researcher from University of South Florida. The author has contributed to research in topics: LDL receptor & HMG-CoA reductase. The author has an hindex of 21, co-authored 29 publications.
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Papers
Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A.
TL;DR: The data confirmed that E2 through the ERs can positively regulate the HDL-R SR-BI through binding and activation of three ERE(1/2) motifs and identified SREBP-1a as a potential coactivator of the E2-ER-dependent effects on the LDL-RSR-BI gene.
Sterol Regulatory Element-Binding Protein-1a Binds to cis Elements in the Promoter of the Rat High Density Lipoprotein Receptor SR-BI Gene
Dayami Lopez,Mark P. McLean +1 more
TL;DR: Western blot analysis found that mature SREBP-1a levels increased up to 11-fold in the ovary after treatment with 50 U hCG, consistent with the possibility that SRE BP- 1a may be involved in the regulation of the HDL receptor SR-BI gene.
Transcriptional repression of the rat steroidogenic acute regulatory (StAR) protein gene by the AP-1 family member c-Fos.
TL;DR: This study is the first to demonstrate that c-Fos represses StAR gene transcription and adds to the current knowledge on the complex relationship that exists between SF-1 and c- Fos in the regulation of StAR activity.
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Transcriptional regulation of rat hepatic low-density lipoprotein receptor and cholesterol 7 alpha hydroxylase by thyroid hormone.
Gene C. Ness,Dayami Lopez +1 more
TL;DR: It is demonstrated that the rapid increase in expression of hepatic low-density lipoprotein (LDL) receptor and cholesterol 7 alpha-hydroxylase in response to thyroid hormone is due to increases in the rates of transcription of these genes.
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Sterol regulatory element binding protein-1a regulation of the steroidogenic acute regulatory protein gene.
TL;DR: Results suggest that SREBP-induced regulation of the rat StAR gene is responsive to selective combinations of transcriptional cofactors that could necessitate the convergence of multiple regulatory pathways to enhance gene transcription.
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