Dawn Walker
University of Sheffield
53 Papers
298 Citations
Dawn Walker is an academic researcher from University of Sheffield. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 20, co-authored 47 publications. Previous affiliations of Dawn Walker include Royal Hallamshire Hospital.
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Papers
The virtual cell—a candidate co-ordinator for ‘middle-out’ modelling of biological systems
Dawn Walker,Jennifer Southgate +1 more
TL;DR: It is demonstrated how cellular-based models have begun to play an important role in the development of 'middle-out' models, but with considerable potential for future development, as well as the application of the paradigm to explore multi-scale phenomena in biology.
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PRIMAGE project : predictive in silico multiscale analytics to support childhood cancer personalised evaluation empowered by imaging biomarkers
Luis Martí-Bonmatí,Angel Alberich-Bayarri,Ruth Ladenstein,Ignacio Blanquer,J. Damian Segrelles,Leonor Cerdá-Alberich,Polyxeni Gkontra,Barbara Hero,José Manuel García-Aznar,Daniel A. Keim,Wolfgang Jentner,Karine Seymour,Ana Jimenez-Pastor,Ismael González-Valverde,Blanca Martínez de las Heras,Samira Essiaf,Dawn Walker,Michel Rochette,Marian Bubak,Jordi Mestres,Marco Viceconti,Gracia Martí-Besa,Adela Cañete,Paul Richmond,Kenneth Y. Wertheim,Tomasz Gubała,Marek Kasztelnik,Jan Meizner,Piotr Nowakowski,Salvador Gilpérez,Amelia Suárez,Mario Aznar,Giuliana Restante,Emanuele Neri +33 more
TL;DR: The decision support prototype will be constructed and validated on two paediatric cancers: neuroblastoma and diffuse intrinsic pontine glioma, and ready for translation to other malignant solid tumours.
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Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium
Saqib Shabir,William Cross,William Cross,Lisa A. Kirkwood,Joanna F. Pearson,Peter A. Appleby,Dawn Walker,Ian Eardley,Ian Eardley,Jennifer Southgate +9 more
TL;DR: The study raises important questions about the ligand selectivity of receptor/channel targets expressed by the urothelium and opens the possibility of selective drug targeting.
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Modelling the electrical impedivity of normal and premalignant cervical tissue
TL;DR: Finite element analysis is used to model the electrical properties of cervical cells in the frequency range 100 Hz-10 MHz and results support clinical data collected with a four electrode pencil probe.
54
Modelling of epithelial tissue impedance measured using three different designs of probe
TL;DR: How the design of the impedance probe affects the ability to discriminate between tissue types is considered, and a new design of probe, which uses a guard electrode to counteract this potential source of variability, is proposed.
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