Dawit Assefa
University of Freiburg
5 Papers
Dawit Assefa is an academic researcher from University of Freiburg. The author has contributed to research in topics: Ascending aorta & Aorta. The author has an hindex of 4, co-authored 5 publications.
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Papers
Complex Plaques in the Proximal Descending Aorta An Underestimated Embolic Source of Stroke
Andreas Harloff,Jan C. Simon,Stefanie M. Brendecke,Dawit Assefa,Thomas Helbing,Alex Frydrychowicz,Johannes Weber,Manfred Olschewski,Christoph Strecker,Jürgen Hennig,Cornelius Weiller,Michael Markl +11 more
TL;DR: In this paper, the authors investigated the incidence of retrograde flow from complex plaques (4mm-thick, ulcerated, or superimposed thrombi) of the descending aorta and its potential role in embolic stroke.
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Adhesion of monocytes to medical steel as used for vascular stents is mediated by the integrin receptor Mac-1 (CD11b/CD18; alphaM beta2) and can be inhibited by semiconductor coating.
Pia Schuler,Dawit Assefa,Jari Ylänne,Nicole Basler,M. Olschewski,Ingo Ahrens,Thomas K. Nordt,Christoph Bode,Karlheinz Peter +8 more
TL;DR: The integrin Mac-1 and its affinity state could be identified as major mediators of monocyte adhesion on medical steel, and it is demonstrated thatMac-1-mediated adhesion of monocytes to stents can be significantly inhibited by silicon carbides of the stent metal.
39
Evidence for a differential functional regulation of the two beta(3)-integrins alpha(V)beta(3) and alpha(IIb)beta(3)
Ingo Ahrens,Niamh Moran,Kelly Aylward,Gerardene Meade,Martin Moser,Dawit Assefa,Desmond J. Fitzgerald,Christoph Bode,Karlheinz Peter +8 more
TL;DR: It is reported that the GFFKR-region of the αV-cytoplasmic domain and in particular two phenylalanines are essential for integrin αVβ3 function, especially for outside–in signaling.
29
Acute pulmonary embolism and a patent foramen ovale: analysis of atrial right-to-left shunting by biphasic transcardiopulmonary thermodilution curves.
TL;DR: A 69-year-old woman with an acute pulmonary embolism developed an intracardiac right-to-left shunt, which was diagnosed early on and quantified via biphasic transcardiopulmonary thermodilution curves.
3D MRI provides improved visualization and detection of aortic arch plaques compared to transesophageal echocardiography.
Andreas Harloff,Stefanie M. Brendecke,Jan C. Simon,Dawit Assefa,Wolf Wallis,Thomas Helbing,Johannes Weber,Alex Frydrychowicz,Werner Vach,Cornelius Weiller,Michael Markl +10 more
TL;DR: 3D magnetic resonance imaging with transesophageal echocardiography (TEE) for the detection of complex aortic plaques (≥4 mm thick, ulcerated, or containing mobile thrombi) is compared.