David L. Gard
California Institute of Technology
4 Papers
126 Citations
David L. Gard is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Vimentin & Sindbis virus. The author has an hindex of 4, co-authored 4 publications.
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Papers
Phosphorylation of intermediate filament proteins by cAMP-dependent protein kinases
TL;DR: The intermediate filament proteins, desmin and vimentin, are phosphorylated in skeletal muscle cells in vivo and are inhibited by the addition of its regulatory subunit, and inhibition is reversed by the presence of cAMP in the reaction mixture.
127
Replication of sindbis virus: VII. Location of 5-methyl cytidine residues in virus-specific RNA
TL;DR: Although there appear to be five specific sites for methylation on the 26 S RNA, only a minority of these sites are modified, as each 26 SRNA molecule contains an average of less than one m^(5)C.
10
The synthesis and distribution of desmin and vimentin during myogenesis in vitro.
David L. Gard,Elias Lazarides +1 more
TL;DR: Electrophoretic and autoradiographic analyses of the incorporation of 35S--methionine into newly synthesized proteins during myogenesis reveal that presumptive chicken myoblasts synthesize primarily one intermediate filament protein: vimentin, and immunofluorescent staining supports the conclusion that desmin is synthesized only in fusing or multinucleate cells.
Biophysical studies on circle formation by Sindbis virus 49 S RNA.
TL;DR: The virion RNA from Semliki Forest virus also forms circles whose t_m value is very similar to that of Sindbis RNA circles, suggesting that the sequences involved in cyclization have been conserved.