David L. Basi
University of Minnesota
20 Papers
154 Citations
David L. Basi is an academic researcher from University of Minnesota. The author has contributed to research in topics: Medicine & Osteonecrosis of the jaw. The author has an hindex of 13, co-authored 20 publications.
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Papers
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis
Goutam Ghosh,Indira V. Subramanian,Neeta Adhikari,Xiaoxiao Zhang,Joshi Hemant,David L. Basi,Y S Chandrashekhar,Jennifer L. Hall,Sabita Roy,Yan Zeng,Sundaram Ramakrishnan +10 more
TL;DR: Evidence for what is believed to be a novel mechanism regulating HIF-1α levels in isolated human ECs during hypoxia is provided and results suggest that miR-322/424 plays an important physiological role in post-ischemic vascular remodeling and angiogenesis.
Bisphosphonate-related osteonecrosis of the jaw: clinical features, risk factors, management, and treatment outcomes of 26 patients.
Vivek Thumbigere-Math,Ma’Ann Sabino,Rajaram Gopalakrishnan,Sabrina Huckabay,Arkadiusz Z. Dudek,Saonli Basu,Pamela J. Hughes,Bryan S. Michalowicz,Joseph W. Leach,Karen K. Swenson,James Q. Swift,Cheryl Adkinson,David L. Basi +12 more
TL;DR: Long-term n-BIS therapy and recent dental procedures are consistent findings in patients withBRONJ, and spontaneous BRONJ lesions respond favorably to current BRonJ treatment strategies.
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A retrospective study evaluating frequency and risk factors of osteonecrosis of the jaw in 576 cancer patients receiving intravenous bisphosphonates.
Vivek Thumbigere-Math,Lam S. Tu,Sabrina Huckabay,Arkadiusz Z. Dudek,Scott Lunos,David L. Basi,Pamela J. Hughes,Joseph W. Leach,Karen K. Swenson,Rajaram Gopalakrishnan +9 more
TL;DR: Increased cumulative doses and long-term BP treatment are the most important risk factors for BRONJ development.
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Matrix Metalloproteinase-9 Expression in Alveolar Extraction Sockets of Zoledronic Acid–Treated Rats
David L. Basi,Pamela J. Hughes,Vivek Thumbigere-Math,Ma’Ann Sabino,Ami Mariash,Scott Lunos,Eric D. Jensen,Rajaram Gopalakrishnan +7 more
TL;DR: ZA reduced bone mineralization within tooth extraction sockets, suggesting aberrant bone healing, and ZA increases the amount and enzymatic activity of MMP-9, while apparently not altering the amount of TIMP1 within extraction sockets.
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Serum Markers of Bone Turnover and Angiogenesis in Patients With Bisphosphonate-Related Osteonecrosis of the Jaw After Discontinuation of Long-Term Intravenous Bisphosphonate Therapy.
Vivek Thumbigere-Math,Bryan S. Michalowicz,Pamela J. Hughes,David L. Basi,Michaela L. Tsai,Karen K. Swenson,Laura Rockwell,Rajaram Gopalakrishnan +7 more
TL;DR: The prolonged skeletal half-life of BPs may suppress bone turnover markers in BRONJ patients for several years after discontinuation of intravenous BP therapy, suggesting an extended effect on bone homeostasis.
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