David J. Edwards
Eli Lilly and Company
4 Papers
15 Citations
David J. Edwards is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Quality of life & Hypopituitarism. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of David J. Edwards include Southampton General Hospital.
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Papers
Stimulated eosinophils and proteinases augment the transepithelial flux of albumin in bovine bronchial mucosa
TL;DR: The observations demonstrate that the ability of eosinophils to injure the bronchial mucosa is independent of the side of the tissue on which they are present, and key aspects of the injury process may be reproduced, at least in part, by metalloproteinases.
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In vitro modulation of the eosinophil-dependent enhancement of the permeability of the bronchial mucosa.
Carolyn A. Herbert,David J. Edwards,David J. Edwards,John R. Boot,John R. Boot,Clive Robinson +5 more
TL;DR: The results suggest that proteinases may make a significant contribution to the genesis of epithelial injury, whereas leukotrienes do not.
Long-Term Improvement of Quality of Life During Growth Hormone (GH) Replacement Therapy in Adults with GH Deficiency, as Measured by Questions on Life Satisfaction-Hypopituitarism (QLS-H)
Myriam Rosilio,Werner F. Blum,David J. Edwards,Elena P. Shavrikova,Domenico Valle,Steven W. J. Lamberts,Eva Marie Erfurth,Susan M. Webb,Richard J. Ross,Kazuo Chihara,Gerhard Henrich,Peter Herschbach,Andrea F. Attanasio +12 more
TL;DR: Improvements in QoL, as measured by the QLS-H, are maintained during long-term GH replacement therapy of adults with GHD, and the Q LS-H is a useful tool for evaluatingQoL in hypopituitary patients treated in clinical practice.
Decreased quality of life in adult patients with growth hormone deficiency compared with general populations using the new, validated, self-weighted questionnaire, questions on life satisfaction hypopituitarism module.
Werner F. Blum,Elena P. Shavrikova,David J. Edwards,Myriam Rosilio,Mark L. Hartman,Fernando Marin,Domenico Valle,Aart Jan van der Lely,Andrea F. Attanasio,Christian J. Strasburger,Gerhard Henrich,Peter Herschbach +11 more
TL;DR: Quality of life assessment in adults with GHD requires the use of z-scores to correct for age, gender, and country differences, and this approach allows pooling of data from different cohorts and comparison with general populations.