David Delaney
Royal National Orthopaedic Hospital
9 Papers
9 Citations
David Delaney is an academic researcher from Royal National Orthopaedic Hospital. The author has contributed to research in topics: Lipoma & Atypical Lipomatous Tumor. The author has an hindex of 9, co-authored 9 publications.
Chat about Author
Papers
Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor
Takeshi Kashima,Dina Halai,Hongtao Ye,Sandra Nalini Hing,David Delaney,Robin Pollock,Paul O'Donnell,Roberto Tirabosco,Adrienne M. Flanagan +8 more
TL;DR: This study assessed whether analysis of MDM2 copy number by fluorescence in situ hybridization (FISH) would help distinguish lipomas from atypical lipomatous tumors, otherwise referred to as well-differentiated liposarcomas, using a commercially availableMDM2 FISH kit.
60
Osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma and adamantinoma: correlation of radiological imaging features with surgical histology and assessment of the use of radiology in contributing to needle biopsy diagnosis.
TL;DR: A diagnosis of classical adamantinoma is suggested by an extensive lesion with moth-eaten margins and complete involvement of the medullary cavity on axial MR imaging, and radiological features can assist in making the correct diagnosis.
54
Familial tumoral calcinosis and hyperostosis-hyperphosphataemia syndrome are different manifestations of the same disease: novel missense mutations in GALNT3.
Leo Joseph,Sandra Nalini Hing,Nadege Presneau,Paul O'Donnell,Paul O'Donnell,Tim C. Diss,Bernadine Idowu,Selvanayagam Joseph,Adrienne M. Flanagan,David Delaney +9 more
TL;DR: The findings from this family add further evidence to the literature that familial tumoral calcinosis and hyperostosis–hyperphosphataemia syndrome are manifestations of the same disease and highlight the importance of appropriate metabolic and genetic investigations.
34
Benefits of molecular pathology in the diagnosis of musculoskeletal disease
Adrienne M. Flanagan,Adrienne M. Flanagan,Adrienne M. Flanagan,David Delaney,Paul O'Donnell,Paul O'Donnell +5 more
TL;DR: The review highlights the range of disease entities classified as “osteoclast-rich lesions,” some of which harbor germline mutations, and addresses the importance of phosphate metabolism in skeletal disorders including phosphaturic mesenchymal tumor, vitamin D-resistant rickets, and tumoral calcinosis.
17
The benefits of molecular pathology in the diagnosis of musculoskeletal disease : part I of a two-part review: soft tissue tumors.
TL;DR: A review of molecular genetic investigations that are available and routinely used by specialist musculoskeletal histopathologists in the diagnosis of neoplastic disease can be found in this paper.
9