David Chia
National University of Singapore
12 Papers
26 Citations
David Chia is an academic researcher from National University of Singapore. The author has contributed to research in topics: Bladder cancer & External beam radiotherapy. The author has an hindex of 4, co-authored 10 publications.
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Papers
Palliative radiotherapy for bladder cancer: a systematic review and meta-analysis.
Jeremy Tey,Francis Ho,Wee Yao Koh,David Chia,Kiat Huat Ooi,Jeffrey Kit Loong Tuan,Balamurugan Vellayappan,Yu Yang Soon +7 more
TL;DR: In this article, the optimal dose fractionation for palliative radiotherapy (RT) in patients with symptomatic advanced bladder cancer is unclear, and the authors aimed to determine if a higher dose of RT was associated with improved symptoms response rates.
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Efficacy of Palliative Bladder Radiotherapy for Hematuria in Advanced Bladder Cancer Using Contemporary Radiotherapy Techniques.
Jeremy Tey,Yu Yang Soon,Timothy Cheo,Kiat Huat Ooi,Francis Ho,Balamurugan Vellayappan,David Chia,Bee Choo Tai +7 more
TL;DR: In this paper, the outcomes of palliative radiotherapy (RT) for hematuria treated with modern RT techniques were reviewed and the primary endpoint was symptom response rate, symptom recurrence rate, overall survival and treatment-related toxicity.
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•Journal Article
Efficacy of palliative bladder radiotherapy for hematuria in advanced bladder cancer using contemporary radiotherapy techniques
Jeremy Tey,Yu Yang Soon,Timothy Cheo,Kiat Huat Ooi,Francis Ho,Balamurugan Vellayappan,David Chia,Bee Choo Tai +7 more
TL;DR: BED regimens should be recommended as they are associated with a significantly lower rate of recurrent hematuria, according to competing risk, as the competing risk showed that patients treated with low BED regimen had 5.76 times the hazard of recurrence compared to high B ED regimen.
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Radical radiotherapy in older patients with muscle invasive bladder cancer.
Caryn Wujanto,Jeremy Tey,David Chia,Francis Ho,Kiat Huat Ooi,Alvin S. Wong,Yu Yang Soon,Keith Lim +7 more
TL;DR: Radical RT is well tolerated in older patients with MIBC and should be considered for curative treatment despite their age, however, careful selection is warranted as frail patients (PS ≥2; SIOG >2) may benefit less.
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Clinical outcomes of fungating breast cancer treated with palliative radiotherapy
David Chia,Ey Tan,Jiade Lu,Yu Yang Soon,Eve Tiong,Timothy Cheo,Keith Hsiu Chin Lim,Jeremy Tey,Johann Tang,Ba Choo,Wee Yao Koh +10 more
TL;DR: High response rates of up to 90 % can be expected, with a median local progression-free survival of 10 months, and higher radiation dose was not found to be associated with a longer duration of palliation or survival.
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