David Carpio

TL;DR: An early rise in CVP after starting an SBT was associated with an increased risk of extubation failure, which might represent a warning signal not captured by usual SBT monitoring and could have relevant clinical implications.

TL;DR: This study supports the hypothesis that where patients are hypovolaemic and awake on scene it might, where possible, be appropriate to delay induction of anaesthesia until after hospital arrival, and shows an association between PHEA and mortality in awake hypotensive trauma patients, which is increased when hypotension is confirmed to be due to Hypovolaemia.

TL;DR: Two different clinical patterns among hyperlactatemic septic shock patients may be identified according to hypoperfusion context, and this provides a starting point to launch further prospective studies to confirm if this approach can lead to a more selective resuscitation strategy.