David C. Wright
University of Alberta
10 Papers
77 Citations
David C. Wright is an academic researcher from University of Alberta. The author has contributed to research in topics: Mitochondrial biogenesis & Adipose tissue. The author has an hindex of 9, co-authored 10 publications. Previous affiliations of David C. Wright include University of Guelph & Université catholique de Louvain.
Chat about Author
Papers
Mechanisms of calcium-induced mitochondrial biogenesis and GLUT4 synthesis
TL;DR: Evidence is provided that the activation of p38 mitogen-activated protein kinase (MAPK) is involved in the pathway through which Ca2+/CaMK mediates mitochondrial and GLUT4 biogenesis, which leads to increases in skeletal muscle mitochondria and glucose transporter 4 (GLUT4) protein content.
80
The effects of apelin treatment on skeletal muscle mitochondrial content.
TL;DR: It is demonstrated that apelin treatment can induce skeletal muscle mitochondrial content through a mechanism that is distinct from that of more robust physiological stressors.
67
Interactions between the consumption of a high-fat diet and fasting in the regulation of fatty acid oxidation enzyme gene expression: an evaluation of potential mechanisms.
TL;DR: The findings suggest that a blunted effect of fasting on the induction of PDK4, MCAD, and UCP3 in skeletal muscle from HFD rats is likely a result of already elevated levels of these enzymes.
50
Increased hypolipidemic benefits of cis -9, trans -11 conjugated linoleic acid in combination with trans -11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA -cp rat
Miriam Jacome-Sosa,Jing Lu,Ye Wang,Megan R. Ruth,David C. Wright,Martin J. T. Reaney,Jianheng Shen,Catherine J. Field,Donna F. Vine,Spencer D. Proctor +9 more
TL;DR: It is demonstrated that the hypolipidemic effects of chronic cis-9, trans-11 CLA supplementation on circulating dyslipidemia and hepatic steatosis are enhanced by the addition of VA in the JCR:LA-cp rat.
Epinephrine-mediated regulation of PDK4 mRNA in rat adipose tissue.
Zhongxiao Wan,A. Brianne Thrush,Melanie Legare,Bruce C. Frier,Lindsey Sutherland,Deon B. Williams,David C. Wright +6 more
TL;DR: The results are the very first to demonstrate an epinephrine-mediated regulation of PDK4 mRNA levels in white adipose tissue and suggest that p38 MAPK and PPARγ could be involved in this pathway.
48