An implantable intraocular physiological sensor (e.g., 2000) for measuring a physiological characteristic, such as intraocular pressure. The implantable intraocular physiological sensor may include a tubular main body (2102) configured to house one or more electrical components. The implantable intraocular physiological sensor may also include a sensor cap (2108) configured to he inserted into a first end of the tubular main body with a moisture barrier seal. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device.

Intraocular physiological sensor

Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.

Drug delivery medical device

A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.

Posterior segment drug delivery

A drug delivery device includes a housing having an interior space, a needle having retracted and deployed states, an injector to move the needle between retracted and deployed states, and a reservoir disposed within the interior space, the reservoir configured to receive a volume of a drug and to be in fluid communication with the needle. The drug delivery device also includes a controller coupled to the injector and the reservoir, and configured to actuate the injector to move the needle from the retracted state to the deployed state only once, and to actuate the reservoir to deliver the volume of the drug to the patient as a single bolus after a preselected time period has elapsed, the controller disposed within the interior space and configured prior to being disposed within the interior space. The delivery device is wearable, disposable, and single-use.

Drug Delivery Device

An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

Methods and apparatus for treating glaucoma

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device

Drug eluting ocular implant

L'invention concerne un capteur physiologique intra-oculaire implantable (par exemple, 200) pour mesurer la pression intra-oculaire, la concentration de glucose dans l'humeur aqueuse et autres caracteristiques physiologiques. Le capteur physiologique intra-oculaire implantable (par exemple, 200) peut etre au moins partiellement alimente par une pile a combustible, telle qu'une pile a combustible a base de glucose electrochimique (par exemple, 210). Le capteur physiologique intra-oculaire implantable (par exemple, 200) peut transmettre de maniere sans fil des mesures a un dispositif externe. En outre, le capteur physiologique intra-oculaire implantable peut incorporer des caracteristiques de drainage aqueux et/ou d'administration de medicament.

Capteur physiologique intra-oculaire

Drug eluting ocular implant with internal plug

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Drug eluting ocular implant

Capteur physiologique intra-oculaire

Drug eluting ocular implant with internal plug