David Apel
University of Marburg
5 Papers
2 Citations
David Apel is an academic researcher from University of Marburg. The author has contributed to research in topics: Signal transduction & Myosin. The author has an hindex of 3, co-authored 5 publications.
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Papers
17β-Estradiol induces supernumerary primordial germ cells in embryos of the polychaete Platynereis dumerilii
Anika Kristin Lidke,Stephanie C Bannister,Andreas Löwer,David Apel,Martina Podleschny,Martin Kollmann,Christian Friedrich Ackermann,Javier García-Alonso,Florian Raible,Nicole Rebscher +9 more
TL;DR: This study reports for the first time an ER mediated proliferative effect of E2 on PGCs in an invertebrate organism and suggests that it is mediated by ER signaling.
19
Evolution of the Rho guanine nucleotide exchange factors Kalirin and Trio and their gene expression in Xenopus development.
TL;DR: A detailed comparative analysis of trio and kalrn expression in Xenopus laevis development is shown, providing first insights into their redundant or distinct functions in a vertebrate model system.
11
Alternative pathways control actomyosin contractility in epitheliomuscle cells during morphogenesis and body contraction.
TL;DR: Analysis of the regional and subcellular localization of the Ser19-phosphorylated myosin regulatory light chain revealed that pMLC20 is induced in these compartments by at least two independent pathways.
3
Bud detachment in hydra requires activation of fibroblast growth factor receptor and a Rho–ROCK–myosin II signaling pathway to ensure formation of a basal constriction
Oliver Holz,David Apel,Patrick R. H. Steinmetz,Ellen Lange,Simon Hopfenmüller,Kerstin Ohler,Stefanie Sudhop,Monika Hassel +7 more
TL;DR: In this article, the authors identify a candidate signaling pathway through Rho, ROCK, and myosin II, which controls bud base constriction and rearrangement of the actin cytoskeleton.
What lies beneath: Hydra provides cnidarian perspectives into the evolution of FGFR docking proteins
Ashwini Suryawanshi,Karolin Schaefer,Oliver Holz,David Apel,Ellen Lange,David C. Hayward,David J. Miller,Monika Hassel +7 more
TL;DR: Gen expression analysis in the cnidarian Hydra revealed that Dof is not upregulated in the zone of strong FGFRa and FGFRb expression at the bud base, indicating a highly conserved toolkit.