Darius A. Schneider
La Jolla Institute for Allergy and Immunology
9 Papers
14 Citations
Darius A. Schneider is an academic researcher from La Jolla Institute for Allergy and Immunology. The author has contributed to research in topics: Type 1 diabetes & Diabetes mellitus. The author has an hindex of 6, co-authored 9 publications. Previous affiliations of Darius A. Schneider include University of California, San Diego.
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Papers
Potential viral pathogenic mechanism in human type 1 diabetes
TL;DR: A summary of experimentally defined viral mechanisms potentially involved in the ontology of type 1 diabetes and some novel hypotheses of how viruses may affect the initiation and natural history of the disease are discussed.
Transient B-Cell Depletion with Anti-CD20 in Combination with Proinsulin DNA Vaccine or Oral Insulin: Immunologic Effects and Efficacy in NOD Mice
Ghanashyam Sarikonda,Sowbarnika Sachithanantham,Yulia Manenkova,Tinalyn Kupfer,Amanda L. Posgai,Clive Wasserfall,Philip Bernstein,Laura Straub,Philippe P. Pagni,Darius A. Schneider,Teresa Rodriguez Calvo,Marilyne Coulombe,Kevan C. Herold,Ronald G. Gill,Mark A. Atkinson,Gerald T. Nepom,Mario R. Ehlers,Teodora Staeva,Hideki Garren,Lawrence Steinman,Andrew C. Chan,Matthias von Herrath +21 more
TL;DR: Combination therapy with anti-CD20 and either oral insulin or proinsulin does not protect hyperglycemic NOD mice, but the combination with proins pancreatic lymph nodes offers limited efficacy in T1D prevention, potentially by augmentation of Proinsulin-specific IL-4 production.
Emerging immune therapies in type 1 diabetes and pancreatic islet transplantation.
TL;DR: Analysing the foundation and the results of the most current T1D immunotherapeutic trials, an outlook for future directions of the field is given.
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Viruses and Type 1 diabetes: a dynamic labile equilibrium.
TL;DR: Analyzing the foundation and the results of the most current work in the field of type 1 diabetes gives a brief overview of current knowledge, as well as providing an outlook for future directions.