Large language models (LLMs) like ChatGPT appear capable of performing a variety of tasks, including answering patient eye care questions, but have not yet been evaluated in direct comparison with ophthalmologists. It remains unclear whether LLM-generated advice is accurate, appropriate, and safe for eye patients.To evaluate the quality of ophthalmology advice generated by an LLM chatbot in comparison with ophthalmologist-written advice.This cross-sectional study used deidentified data from an online medical forum, in which patient questions received responses written by American Academy of Ophthalmology (AAO)-affiliated ophthalmologists. A masked panel of 8 board-certified ophthalmologists were asked to distinguish between answers generated by the ChatGPT chatbot and human answers. Posts were dated between 2007 and 2016; data were accessed January 2023 and analysis was performed between March and May 2023.Identification of chatbot and human answers on a 4-point scale (likely or definitely artificial intelligence [AI] vs likely or definitely human) and evaluation of responses for presence of incorrect information, alignment with perceived consensus in the medical community, likelihood to cause harm, and extent of harm.A total of 200 pairs of user questions and answers by AAO-affiliated ophthalmologists were evaluated. The mean (SD) accuracy for distinguishing between AI and human responses was 61.3% (9.7%). Of 800 evaluations of chatbot-written answers, 168 answers (21.0%) were marked as human-written, while 517 of 800 human-written answers (64.6%) were marked as AI-written. Compared with human answers, chatbot answers were more frequently rated as probably or definitely written by AI (prevalence ratio [PR], 1.72; 95% CI, 1.52-1.93). The likelihood of chatbot answers containing incorrect or inappropriate material was comparable with human answers (PR, 0.92; 95% CI, 0.77-1.10), and did not differ from human answers in terms of likelihood of harm (PR, 0.84; 95% CI, 0.67-1.07) nor extent of harm (PR, 0.99; 95% CI, 0.80-1.22).In this cross-sectional study of human-written and AI-generated responses to 200 eye care questions from an online advice forum, a chatbot appeared capable of responding to long user-written eye health posts and largely generated appropriate responses that did not differ significantly from ophthalmologist-written responses in terms of incorrect information, likelihood of harm, extent of harm, or deviation from ophthalmologist community standards. Additional research is needed to assess patient attitudes toward LLM-augmented ophthalmologists vs fully autonomous AI content generation, to evaluate clarity and acceptability of LLM-generated answers from the patient perspective, to test the performance of LLMs in a greater variety of clinical contexts, and to determine an optimal manner of utilizing LLMs that is ethical and minimizes harm. 

Comparison of Ophthalmologist and Large Language Model Chatbot Responses to Online Patient Eye Care Questions

In this paper, we introduce a unified and generalist Biomedical Generative Pre-trained Transformer (BiomedGPT) model, which leverages self-supervision on large and diverse datasets to accept multi-modal inputs and perform a range of downstream tasks. Our experiments demonstrate that BiomedGPT delivers expansive and inclusive representations of biomedical data, outperforming the majority of preceding state-of-the-art models across five distinct tasks with 20 public datasets spanning over 15 unique biomedical modalities. Through the ablation study, we also showcase the efficacy of our multi-modal and multi-task pretraining approach in transferring knowledge to previously unseen data. Overall, our work presents a significant step forward in developing unified and generalist models for biomedicine, with far-reaching implications for improving healthcare outcomes.

pdf/biomedgpt-a-unified-and-generalist-biomedical-generative-pre-nm9ptb2c.pdf

BiomedGPT: A Unified and Generalist Biomedical Generative Pre-trained Transformer for Vision, Language, and Multimodal Tasks

Design an efficient VARMA LSTM GRU model for identification of deep-fake images via dynamic window-based spatio-temporal analysis

In this paper, we introduce a unified and generalist Biomedical Generative Pre-trained Transformer (BiomedGPT) model, which leverages self-supervision on large and diverse datasets to accept multi-modal inputs and perform a range of downstream tasks. Our experiments demonstrate that BiomedGPT delivers expansive and inclusive representations of biomedical data, outperforming the majority of preceding state-of-the-art models across five distinct tasks with 20 public datasets spanning over 15 unique biomedical modalities. Through the ablation study, we also showcase the efficacy of our multi-modal and multi-task pretraining approach in transferring knowledge to previously unseen data. Overall, our work presents a significant step forward in developing unified and generalist models for biomedicine, with far-reaching implications for improving healthcare outcomes. 

/pdf/biomedgpt-a-unified-and-generalist-biomedical-generative-pre-1m4quzae.pdf

BiomedGPT: A Unified and Generalist Biomedical Generative Pre-trained
  Transformer for Vision, Language, and Multimodal Tasks

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of medical data, these models are hardly adopted in clinical workflows, mainly due to their lack of interpretability. The black-box-ness of deep learning models has raised the need for devising strategies to explain the decision process of these models, leading to the creation of the topic of eXplainable Artificial Intelligence (XAI). In this context, we provide a thorough survey of XAI applied to medical imaging diagnosis, including visual, textual, example-based and concept-based explanation methods. Moreover, this work reviews the existing medical imaging datasets and the existing metrics for evaluating the quality of the explanations. In addition, we include a performance comparison among a set of report generation-based methods. Finally, the major challenges in applying XAI to medical imaging and the future research directions on the topic are also discussed.

pdf/explainable-deep-learning-methods-in-medical-image-43xsvk56wd.pdf

Explainable Deep Learning Methods in Medical Image Classification: A Survey

The proposed model for automatic clinical image caption generation combines the analysis of radiological scans with structured patient information from the textual records. It uses two language models, the Show-Attend-Tell and the GPT-3, to generate comprehensive and descriptive radiology records. The generated textual summary contains essential information about pathologies found, their location, along with the 2D heatmaps that localize each pathology on the scans. The model has been tested on two medical datasets, the Open-I, MIMIC-CXR, and the general-purpose MS-COCO, and the results measured with natural language assessment metrics demonstrated its efficient applicability to chest X-ray image captioning. 

/pdf/medical-image-captioning-via-generative-pretrained-1b4uvo67.pdf

Medical image captioning via generative pretrained transformers

Deep fake stands for a face swapping algorithm where the source and target can be an image or a video. Researchers have investigated sophisticated generative adversarial networks (GAN), autoencoders, and other approaches to establish precise and robust algorithms for face swapping. However the achieved results are far from perfect in terms of human and visual evaluation. In this study, we propose a new one-shot pipeline for image-to-image and image-to-video face swap solutions - GHOST (Generative High-fidelity One Shot Transfer). We take the FaceShifter (image-to-image) architecture as a baseline approach and propose several major architecture improvements which include a new eye-based loss function, face mask smooth algorithm, a new face swap pipeline for image-to-video face transfer, a new stabilization technique to decrease face jittering on adjacent frames and a super-resolution stage. In the experimental stage, we show that our solution outperforms SoTA face swap architectures in terms of ID retrieval (+1.5% improvement), shape (the second best value) and eye gaze preserving (+1% improvement) metrics. We also established an ablation study for our solution to estimate the contribution of pipeline stages to the overall accuracy, which showed that the eye loss leads to 2% improvement in the ID retrieval and 45% improvement in the eye gaze preserving.

GHOST—A New Face Swap Approach for Image and Video Domains

Deep fake technology became a hot field of research in the last few years. Researchers investigate sophisticated Generative Adversarial Networks (GAN), autoencoders, and other approaches to establish precise and robust algorithms for face swapping. Achieved results show that the deep fake unsupervised synthesis task has problems in terms of the visual quality of generated data. These problems usually lead to high fake detection accuracy when an expert analyzes them. The first problem is that existing image-to-image approaches do not consider video domain specificity and frame-by-frame processing leads to face jittering and other clearly visible distortions. Another problem is the generated data resolution, which is low for many existing methods due to high computational complexity. The third problem appears when the source face has larger proportions (like bigger cheeks), and after replacement it becomes visible on the face border. Our main goal was to develop such an approach that could solve these problems and outperform existing solutions on a number of clue metrics. We introduce a new face swap pipeline that is based on FaceShifter architecture and fixes the problems stated above. With a new eye loss function, super-resolution block, and Gaussian-based face mask generation leads to improvements in quality which is confirmed during evaluation.

A new face swap method for image and video domains: a technical report

In the report we propose six new implementations of ruCLIP model trained on our 240M pairs. The accuracy results are compared with original CLIP model with Ru-En translation (OPUS-MT) on 16 datasets from different domains. Our best implementations outperform CLIP + OPUS-MT solution on most of the datasets in few-show and zero-shot tasks. In the report we briefly describe the implementations and concentrate on the conducted experiments. Inference execution time comparison is also presented in the report.

RuCLIP - new models and experiments: a technical report

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Daniil Chesakov

Author Tools

Chat about Author

Papers

Medical image captioning via generative pretrained transformers

GHOST—A New Face Swap Approach for Image and Video Domains

A new face swap method for image and video domains: a technical report

RuCLIP - new models and experiments: a technical report