Danielle Yi
Institute for Systems Biology
5 Papers
28 Citations
Danielle Yi is an academic researcher from Institute for Systems Biology. The author has contributed to research in topics: Regulation of gene expression & Gene expression profiling. The author has an hindex of 5, co-authored 5 publications.
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Papers
RNASEQR—a streamlined and accurate RNA-seq sequence analysis program
Leslie Y. Chen,Kuo-Chen Wei,Abner C. Y. Huang,Kai Wang,Chiung-Yin Huang,Danielle Yi,Chuan Yi Tang,David J. Galas,Leroy Hood +8 more
TL;DR: RNASEQR analyzes raw data from RNA-seq experiments effectively and outputs results in a manner that is compatible with a wide variety of specialized downstream analyses on desktop computers, as well as more accurate detection of single nucleotide variants (SNVs).
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RNASEQR - A streamlined and accurate RNA-seq sequence analysis program
Abner C. Y. Huang,Leslie Y. Chen,Kuo-Chen Wei,Kai Wang,Chiung-Yin Huang,Danielle Yi,Chuan Yi Tang,David J. Galas,Leroy Hood +8 more
TL;DR: RNASEQR as discussed by the authors is based on the initial genome localization and alignment information for RNA-seq sequences, and it has been shown to yield more accurate estimates for gene expression, complete gene structures and new transcript isoforms, as well as more accurate detection of single nucleotide variants.
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A CD133-related gene expression signature identifies an aggressive glioblastoma subtype with excessive mutations
Xiaowei Yan,Li Ma,Danielle Yi,Jae Geun Yoon,Alan H. Diercks,Gregory Foltz,Nathan D. Price,Leroy Hood,Qiang Tian,Qiang Tian +9 more
TL;DR: Molecular and genetic support is provided for the stem cell-like nature of CD133+ cells and an objective means for evaluating cancer aggressiveness and the CD133 gene signature distinguishes higher-grade breast and bladder cancers from their lower-grade counterparts.
Single-cell analyses demonstrate that a heme–GATA1 feedback loop regulates red cell differentiation
Raymond T. Doty,Xiaowei Yan,Christopher Lausted,Adam D. Munday,Zhantao Yang,Danielle Yi,Neda Jabbari,Li Liu,Sioban Keel,Qiang Tian,Janis L. Abkowitz +10 more
TL;DR: Observations reveal a GATA1-heme autoregulatory loop and implicate GATA2 and heme as the comaster regulators of the normal erythroid differentiation program, and may help explain the ineffective (early termination of) erythropoiesis in Diamond Blackfan anemia and del(5q) myelodysplasia.
Integrated Expression Profiling and ChIP-seq Analyses of the Growth Inhibition Response Program of the Androgen Receptor
Biaoyang Lin,Jun Wang,Xu Hong,Xiaowei Yan,Daehee Hwang,Ji-Hoon Cho,Danielle Yi,Angelita G. Utleg,Xuefeng Fang,Dustin E. Schones,Keji Zhao,Gilbert S. Omenn,Leroy Hood +12 more
TL;DR: The data provide a valuable data set in understanding the molecular basis for growth inhibition response program of the AR in prostate cancer cells, which can be exploited for developing novel prostate cancer therapeutic strategies.