Daniela Segat
University of Padua
16 Papers
324 Citations
Daniela Segat is an academic researcher from University of Padua. The author has contributed to research in topics: Ormosil & Proinflammatory cytokine. The author has an hindex of 13, co-authored 15 publications.
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Papers
Bronchopulmonary carcinoid: phenotype and long-term outcome in a single-institution series of Italian patients.
Massimo Rugge,Matteo Fassan,Roberto Clemente,Giovanna Rizzardi,Luciano Giacomelli,Gianmaria Pennelli,Claudia Mescoli,Daniela Segat,Federico Rea +8 more
TL;DR: Mib1 and Bcl2 significantly discriminate between recurrent versus nonrecurrent tumors, producing a biologically plausible, diagnostically suitable immunohistochemical pattern.
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Highly PEGylated silica nanoparticles: “ready to use” stealth functional nanocarriers
Iria Maria Rio-Echevarria,Francesco Selvestrel,Daniela Segat,Gaetano Guarino,Regina Tavano,Valerio Causin,Elena Reddi,Emanuele Papini,Fabrizio Mancin +8 more
TL;DR: A new procedure to prepare doped and PEGylated silica-based nanoparticles with absence of cytotoxicity and “stealth” behaviour toward phagocytic capture by human macrophages has been demonstrated and this enables such nanosystems as candidates for the development of drug delivery agents.
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Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles
Regina Tavano,Daniela Segat,Elena Reddi,Janko Kos,Matija Rojnik,Petra Kocbek,Selma Iratni,Dietrich Scheglmann,Mario Colucci,Iria M. Rio Echevarria,Francesco Selvestrel,Fabrizio Mancin,Emanuele Papini +12 more
TL;DR: Stealth, highly PEGylated ORMOSIL-NPs with a poor procoagulant activity can be used as starting blocks to design hemocompatible nanomedical-devices.
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The functional dissection of the plasma corona of SiO₂-NPs spots histidine rich glycoprotein as a major player able to hamper nanoparticle capture by macrophages.
Chiara Fedeli,Daniela Segat,Regina Tavano,Luigi Bubacco,Giorgia De Franceschi,Patrizia Polverino de Laureto,Elisa Lubian,Francesco Selvestrel,Fabrizio Mancin,Emanuele Papini +9 more
TL;DR: Histidine Rich Glycoprotein (HRG) is the most abundant component of the SiO2-NP hard corona in excess plasma from humans (HP) and mice (MP), together with minor amounts of the homologous Kininogen-1 (Kin-1), while it is remarkably absent in their Foetal Calf Serum (FCS)-derived corona.
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Selection of multipotent cells and enhanced muscle reconstruction by myogenic macrophage-secreted factors.
Alberto Malerba,Libero Vitiello,Daniela Segat,Emanuela Dazzo,Marco Frigo,Ilaria Scambi,Paolo De Coppi,Luisa Boldrin,Laura Martelli,Alessandra Pasut,Chiara Romualdi,Rosa Grazia Bellomo,Jacopo Vecchiet,Maurizio David Baroni +13 more
TL;DR: It is shown that in the presence of a murine macrophage conditioned medium (mMCM), a subpopulation of multipotent cells could be selected and expanded from adult rat muscle and showed mesenchymal differentiation plasticity, suggesting that macrophagic factors could be of great help in developing therapeutic protocols with myogenic stem cells.
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