Daniela Pezzolla
University of Oxford
8 Papers
33 Citations
Daniela Pezzolla is an academic researcher from University of Oxford. The author has contributed to research in topics: Embryonic stem cell & Cellular differentiation. The author has an hindex of 5, co-authored 8 publications. Previous affiliations of Daniela Pezzolla include Spanish National Research Council & Dresden University of Technology.
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Papers
Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
Filipa C. Simões,Thomas J. Cahill,Amy Kenyon,Daria Gavriouchkina,Daria Gavriouchkina,Joaquim M. Vieira,Xin Sun,Daniela Pezzolla,Christophe Ravaud,Eva Masmanian,Michael Weinberger,Sarah Mayes,Madeleine E. Lemieux,Damien N. Barnette,Mala Gunadasa-Rohling,Ruth M. Williams,David R. Greaves,Le A. Trinh,Scott E. Fraser,Sarah L. Dallas,Robin P. Choudhury,Tatjana Sauka-Spengler,Paul R. Riley +22 more
TL;DR: An evolutionarily-conserved function of macrophages is identified that contributes directly to the forming post-injury scar through cell-autonomous deposition of collagen.
298
Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
Daniela Pezzolla,Javier López-Beas,Christian Claude Lachaud,Alejandro Domínguez-Rodríguez,Tarik Smani,Abdelkrim Hmadcha,Bernat Soria +6 more
TL;DR: An efficient differentiation protocol is optimized that allows the efficient differentiation of hESCs into pancreatic endoderm capable of generating β-cell-like cells and demonstrates that RSV improves the maturation process.
Functional vascular smooth muscle-like cells derived from adult mouse uterine mesothelial cells.
Christian Claude Lachaud,Daniela Pezzolla,Alejandro Domínguez-Rodríguez,Tarik Smani,Bernat Soria,Abdelkrim Hmadcha +5 more
TL;DR: It is shown for the first time that UtMCs could recapitulate in vitro differentiative events of early cardiovascular differentiation and transdifferentiate in cells exhibiting molecular and functional characteristics of VSMCs.
Zebularine regulates early stages of mESC differentiation: effect on cardiac commitment.
A Horrillo,Daniela Pezzolla,Mario F. Fraga,Yolanda Aguilera,C Salguero-Aranda,Juan R. Tejedo,Franz Martín,Francisco J. Bedoya,Bernat Soria,Abdelkrim Hmadcha +9 more
TL;DR: The results indicate that zebularine regulates mesodermal differentiation of mESCs, controls promoter methylation of crucial cardiac genes and may help to improve cardiomyogenic differentiation.
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Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression.
Ioannis Giannios,Ioannis Serafimidis,Vivian Anastasiou,Daniela Pezzolla,Mathias Lesche,Cordula Andree,Marc Bickle,Anthony Gavalas +7 more
TL;DR: The findings implicated methyltransferase activity in the regulation of endocrine differentiation and showed that methyltransferases can act through specific regulators during pancreas differentiation.
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