Daniela Olivera
Imperial College London
5 Papers
24 Citations
Daniela Olivera is an academic researcher from Imperial College London. The author has contributed to research in topics: Inflammasome & Medicine. The author has an hindex of 2, co-authored 2 publications.
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Papers
Report 20: Using mobility to estimate the transmission intensity of COVID-19 in Italy: A subnational analysis with future scenarios
Michaela A. C. Vollmer,Swapnil Mishra,H. Juliette T. Unwin,Axel Gandy,Thomas A. Mellan,Valerie C. Bradley,Harrison Zhu,Helen Coupland,Iwona Hawryluk,Michael Hutchinson,Oliver Ratmann,Melodie Monod,Patrick G T Walker,C. R. Whittaker,Lorenzo Cattarino,Constance Ciavarella,Lucia Cilloni,Kylie E. C. Ainslie,Marc Baguelin,Sangeeta N. Bhatia,A Boonyasiri,Nicholas F Brazeau,Giovanni Charles,Laura V Cooper,Zulma M. Cucunubá,Gina Cuomo-Dannenburg,Amy Dighe,Bimandra A Djaafara,Jeff Eaton,Sabine L van Elsland,Richard G. FitzJohn,K. J. Fraser,Katy A. M. Gaythorpe,W Green,Sarah Hayes,Natsuko Imai,Ben Jeffrey,Edward Knock,Daniel J Laydon,John A. Lees,Tara D. Mangal,Andria Mousa,Gemma Nedjati-Gilani,Pierre Nouvellet,Daniela Olivera,Kris V Parag,Michael Pickles,Hayley A Thompson,Robert Verity,Caroline E. Walters,Haowei Wang,Y Wang,Oliver J Watson,Lilith K Whittles,Xiaoyue Xi,Azra A M Ghani,Steven Riley,Lucy C Okell,Christl A. Donnelly,Neil M. Ferguson,Ilaria Dorigatti,Seth Flaxman,Samir Bhatt +62 more
TL;DR: It is found that, in the absence of additional interventions, even a 20% return to pre-lockdown mobility could lead to a resurgence in the number of deaths far greater than experienced in the current wave in several regions.
Subnational analysis of the COVID-19 epidemic in Brazil
Thomas A. Mellan,Henrique Hoeltgebaum,Swapnil Mishra,Charles Whittaker,Ricardo P Schnekenberg,Axel Gandy,H. Juliette T. Unwin,Michaela A. C. Vollmer,Helen Coupland,Iwona Hawryluk,Nuno R. Faria,Juan F. Vesga,Harrison Zhu,Michael Hutchinson,Oliver Ratmann,Melodie Monod,Kylie E. C. Ainslie,Marc Baguelin,Sangeeta N. Bhatia,A Boonyasiri,Nicholas F Brazeau,Giovanni Charles,Laura V Cooper,Zulma M. Cucunubá,Gina Cuomo-Dannenburg,Amy Dighe,Bimandra A Djaafara,Jeff Eaton,Sabine L. van Elsland,Richard G. FitzJohn,Keith J. Fraser,Katy A. M. Gaythorpe,W Green,Sarah Hayes,Natsuko Imai,Ben Jeffrey,Edward Knock,Daniel J Laydon,John A. Lees,Tara D. Mangal,Andria Mousa,Gemma Nedjati-Gilani,Pierre Nouvellet,Daniela Olivera,Kris V Parag,Michael Pickles,Hayley A Thompson,Robert Verity,Caroline E. Walters,Haowei Wang,Y Wang,Oliver J Watson,Lilith K Whittles,Xiaoyue Xi,Lucy C Okell,Ilaria Dorigatti,Patrick G T Walker,Azra C. Ghani,Steven Riley,Neil M. Ferguson,Christl A. Donnelly,Seth Flaxman,Samir Bhatt +62 more
TL;DR: In this paper, the authors characterised the initial dynamics of COVID-19 across the country and assessed the impact of non-pharmaceutical interventions (NPIs) that were implemented using a semi-mechanistic Bayesian hierarchical modelling approach.
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PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
Maite Duhalde Vega,Daniela Olivera,Gustavo Gastão Davanzo,Mauricio Bertullo,Verónica Noya,Gabriela Fabiano de Souza,Stéfanie Primon Muraro,Ícaro Maia Santos de Castro,Ana Paula Arévalo,Martina Crispo,Germán Galliussi,Sofía Russo,David Charbonnier,Florencia Rammauro,Mathias Jeldres,Catalina Alamón,Valentina Varela,Carlos Batthyány,Mariela Bollati-Fogolín,Pablo Oppezzo,Otto Pritsch,José Luiz Proença-Módena,Helder I. Nakaya,Emiliano Trias,Luis Barbeito,Ignacio Anegon,Maria-Cristina Cuturi,Pedro M. Moraes-Vieira,Mercedes Segovia,Marcelo Hill +29 more
TL;DR: In critical COVID-19, inflammasome activation correlated with dysfunctional T cells and low monocytic TMEM176B expression, whereas PD-L1 blockade rescued T cell functionality, supporting a cancer immunotherapy to reinforce T cell immunity in critical β-coronavirus disease.
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The intracellular cation channel TMEM176B as a dual immunoregulator
TL;DR: How expression data, clinical associations of genetic variants and functional studies support a dual role for TMEM176B in regulating immune responses, and recent data on modulation of DC biology and inflammasome activation as well as CD8+ T cell responses are reviewed.
Formulating a TMEM176B blocker in nanoparticles uncouples its paradoxical roles in innate and adaptive antitumoral immunity
Sabina Victoria,Analía Castro,Álvaro Pittini,Daniela Olivera,Sofía Russo,Ignacio Cebrian,Alvaro W. Mombrú,Eduardo Osinaga,Helena Pardo,Mercedes Segovia,Marcelo Hill +10 more
TL;DR: Overall, rationally developed a formulating method of BayK8644 that improves its anti-tumoral therapeutic efficacy by uncoupling the dual role of TMEM176B on innate and adaptive immunity.
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