Daniel Shin
Brigham and Women's Hospital
6 Papers
54 Citations
Daniel Shin is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Immunology & Epitope. The author has an hindex of 2, co-authored 2 publications.
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Papers
Discordant QuantiFERON-TB Gold test results among US healthcare workers with increased risk of latent tuberculosis infection: a problem or solution?
Nira R. Pollock,Antonio Campos-Neto,Suely S. Kashino,Danielle R. Napolitano,Samuel M. Behar,Daniel Shin,Alexander Sloutsky,Swati Joshi,Jasmine Guillet,Michael Wong,Edward A. Nardell +10 more
TL;DR: Results of extended stimulation assays suggest that many of the authors' IR HCWs have indeed been sensitized to Mycobacterium tuberculosis, and raises concern about the sensitivity of the QFT-G assay for detection of LTBI in their HCWs.
SARS-CoV-2 epitope-specific CD4+ memory T cell responses across COVID-19 disease severity and antibody durability
Ryan W. Nelson,Yuezhou Chen,Olivia L. Venezia,Richard Majerus,Daniel Shin,Mary Carrington,Duane R. Wesemann,James J. Moon,Andrew D. Luster,B. A. Abayneh,P. Allen,Galit Alter,Diane Antille,Katrina L Armstrong,Alejandro B. Balazs,Julia Bals,M. Barbash,Yannic C. Bartsch,Julie Boucau,Siobhan Boyce,Janet F. Braley,Karen Marie Coperich Branch,Katherine Broderick,J. Carney,Andrew T. Chan,Josh Chevalier,Fatema Z. Chowdhury,George Q. Daley,Susan P. Davidson,Michael Dougan,D. A. Drew,Kevin Einkauf,Ashley Elliman,Jonathan K. Fallon,Liz Fedirko,Kelsey K. Finn,Keith T. Flaherty,Jeanne Flannery,Pamela J. Forde,Pilar Garcia-Broncano,Elise Gettings,David E. Golan,Amanda J. Griffin,Sheila Grimmel,Kathleen A. Grinke,Kathryn T. Hall,Ciputra Adijaya Hartana,Michael D. Healy,H. Heller,Deborah Henault,Grace Holland,Chenyang Jiang,Nikolaus Jilg,Paulina Kaplonek,Marshall Karpell,Chantal Kayitesi,Evan C. Lam,V Roberto Lavalle,Kristina Lefteri,Xiao-Mei Lian,Mathias Lichterfeld,Daniel Lingwood,Huan Liu,Jinqing Liu,Yuting Lu,Sarah Luthern,N. Ly,J. Marchewka,Brittani Martino,R. McNamara,Ashlin R. Michell,Ilan Millstrom,Noah Miranda,Christian Nambu,S. Nelson,Marjorie Noone,Claire O'Callaghan,Christine Ommerborn,Matthew Osborn,Lois Chris Pacheco,Nicole Phan,Shiv Pillai,F. A. Porto,Yelizaveta Rassadkina,Alexandra Reissis,Alexandra Rosenthal,Francis Ruzicka,Edward Francis Ryan,Kyra Seiger,K. Selleck,Libera Sessa,Arlene H. Sharpe,Christianne Sharr,Sally Shin,Nishant K. Singh,Sue Slaughenhaupt,Kim Sheppard,Weiwei Sun,Xiaoming Sun,Elizabeth Suschana,Hannah J. Ticheli,Alicja Trocha-Piechocka,Vivine Wilson,Colline Wong,Daniel P Worrall,Alex Lee Zhu,Zachary Manickas-Hill,Edward Demers,Kelly Judge,Musie Ghebremichael,Peggy S Lai,Jonathan Z. Li,Bruce D. Walker,Maureen P. Martin,Yuko Yuki +114 more
TL;DR: Analysis of SARS-CoV-2-specific CD4+ T cells responses in a subset of individuals with sustained anti-S antibody responses following viral clearance also revealed an increased proportion of memory cTfh cells, indicating efficient early disease control also predicts favorable long-term adaptive immunity.
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Mycobacterium tuberculosis Directs Immunofocusing of CD8+ T Cell Responses Despite Vaccination
Joshua S. Woodworth,Daniel Shin,Mattijs Volman,Cláudio Nunes-Alves,Sarah M. Fortune,Samuel M. Behar,Samuel M. Behar +6 more
TL;DR: It is speculated that factors intrinsic to the chronic nature of M. tuberculosis infection establishes the hierarchy of immunodominance and may explain the failure of some vaccines to provide protection.
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Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells.
Daniel Shin,Sneha Ratnapriya,Creel Ng Cashin,Lucy F. Kuhn,Rod A. Rahimi,Robert M. Anthony,James J. Moon +6 more
TL;DR: The self-antigen-specific CD4+ T cell repertoire is poised to serve a regulatory function during acute tissue damage to limit further damage and the possibility of autoimmunity.
11
Lung injury induces a polarized immune response by self antigen-specific Foxp3+ regulatory T cells
Daniel Shin,Sneha Ratnapriya,Creel Ng Cashin,Lucy F. Kuhn,Rod A. Rahimi,Robert M. Anthony,James J. Moon +6 more
TL;DR: This paper used peptide:MHCII tetramers to track the behavior of endogenous CD4+ T cells with specificity to a lung-expressed self antigen in mouse models of immune-mediated lung injury.