Daniel Keifenheim
University of Massachusetts Medical School
15 Papers
18 Citations
Daniel Keifenheim is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Mitosis & Schizosaccharomyces pombe. The author has an hindex of 6, co-authored 14 publications. Previous affiliations of Daniel Keifenheim include University of Minnesota.
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Papers
Comparative functional genomics of the fission yeasts
Nicholas Rhind,Zehua Chen,Moran Yassour,Moran Yassour,Dawn Thompson,Brian J. Haas,Naomi Habib,Ilan Wapinski,Ilan Wapinski,Sushmita Roy,Michael F. Lin,David I. Heiman,Sarah Young,Kanji Furuya,Yabin Guo,Alison L. Pidoux,Huei Mei Chen,Barbara Robbertse,Jonathan M. Goldberg,Keita Aoki,Elizabeth H. Bayne,Aaron M. Berlin,Christopher A. Desjardins,Edward Dobbs,Livio Dukaj,Lin Fan,Michael Fitzgerald,Courtney French,Sharvari Gujja,Klavs R. Hansen,Daniel Keifenheim,Joshua Z. Levin,Rebecca A. Mosher,Carolin A. Müller,Jenna Pfiffner,Margaret Priest,Carsten Russ,Agata Smialowska,Agata Smialowska,Peter Swoboda,Sean M. Sykes,Matthew W. Vaughn,Sonya Vengrova,Ryan J. Yoder,Qiandong Zeng,Robin C. Allshire,David C. Baulcombe,Bruce W. Birren,William Brown,Karl Ekwall,Karl Ekwall,Manolis Kellis,Janet Leatherwood,Henry L. Levin,Hanah Margalit,Robert A. Martienssen,Conrad A. Nieduszynski,Joseph W. Spatafora,Nir Friedman,Jacob Z. Dalgaard,Peter Baumann,Peter Baumann,Peter Baumann,Hironori Niki,Aviv Regev,Aviv Regev,Chad Nusbaum +66 more
TL;DR: Differences in gene content and regulation explain why, unlike the budding yeast of Saccharomycotina, fission yeasts cannot use ethanol as a primary carbon source and provide tools for investigation across the Schizosaccharomyces clade.
Size-Dependent Expression of the Mitotic Activator Cdc25 Suggests a Mechanism of Size Control in Fission Yeast
Daniel Keifenheim,Xi-Ming Sun,Edridge D'Souza,Makoto J. Ohira,Mira Magner,Michael B. Mayhew,Samuel Marguerat,Nicholas Rhind +7 more
TL;DR: Evidence is presented that cell size in the fission yeast Schizosaccharomyces pombe is regulated by a third strategy: the size-dependent expression of the mitotic activator Cdc25, which may provide a widespread solution to the problem of size control in eukaryotes.
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A noncatalytic function of the topoisomerase II CTD in Aurora B recruitment to inner centromeres during mitosis
Heather Edgerton,Marnie Johansson,Daniel Keifenheim,Soumya Mukherjee,Jeremy M. Chacón,Jeff Bachant,Melissa K. Gardner,Duncan J. Clarke +7 more
TL;DR: The role of the Topo II CTD during mitosis in yeast is resolved, showing that it functions noncatalytically via the Haspin-H3 T3-Phos pathway to recruit Ipl1/Aurora B to mitotic inner centromeres.
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Topoisomerase II SUMOylation activates a metaphase checkpoint via Haspin and Aurora B kinases.
Nootan Pandey,Daniel Keifenheim,Makoto Michael Yoshida,Victoria A. Hassebroek,Caitlin Soroka,Yoshiaki Azuma,Duncan J. Clarke +6 more
TL;DR: To prevent chromosome missegregation, a metaphase checkpoint is activated when topoisomerase II is catalytically inhibited and DNA catenations persist.
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Fission yeast nucleolar protein Dnt1 regulates G2/M transition and cytokinesis by downregulating Wee1 kinase
Zhi yong Yu,Meng ting Zhang,Gao yuan Wang,Dan Xu,Daniel Keifenheim,Alejandro Franco,José Cansado,Hirohisa Masuda,Nicholas Rhind,Yamei Wang,Quan-Wen Jin +10 more
TL;DR: It is shown that dnt1+ positively regulates G2/M transition during the cell cycle and an unexpected missing link between the nucleolar protein Dnt1 and the SIN signaling pathway, which is mediated by the Cdk1 regulator Wee1 kinase is revealed.
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