Daniel F. Milano
Northeastern University
7 Papers
12 Citations
Daniel F. Milano is an academic researcher from Northeastern University. The author has contributed to research in topics: Cancer cell & Cancer. The author has an hindex of 4, co-authored 7 publications. Previous affiliations of Daniel F. Milano include University of New Hampshire.
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Papers
Palladium–Tin Alloyed Catalysts for the Ethanol Oxidation Reaction in an Alkaline Medium
TL;DR: In this paper, a series of carbon-supported Pd-Sn binary alloyed catalysts were used as anode electrocatalysts for direct ethanol fuel cell reactions in an alkaline medium.
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Regulators of Metastasis Modulate the Migratory Response to Cell Contact under Spatial Confinement
Daniel F. Milano,Nicholas Ngai,Senthil K. Muthuswamy,Senthil K. Muthuswamy,Anand R. Asthagiri +4 more
TL;DR: The characteristic fibrillar dimension (CFD) at which effective sliding is achieved is proposed as a metric of sliding ability under spatial confinement and it is demonstrated that sliding is a quantitative property and a decrease in CFD is an effective metric to understand how multiple genetic hits interact to change cell behavior in fibrillsar environments.
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Engineering cell–cell signaling
TL;DR: Significant advances in engineering juxtacrine signaling lay a strong foundation for an integrative approach to utilize synthetic cells, advanced 'chassis' and predictive modeling to engineer the form and function of living tissues.
11
Positive Quantitative Relationship between EMT and Contact-Initiated Sliding on Fiber-like Tracks
Daniel F. Milano,Robert J Natividad,Yasuhiro Saito,Catherine Y. Luo,Senthil K. Muthuswamy,Anand R. Asthagiri +5 more
TL;DR: It is shown that EMT-associated invasive sliding is progressive, with cells that undergo partial EMT exhibiting intermediate sliding behavior and cells that transition more completely through EMT displaying maximal sliding, suggesting a model in which fiber maturation and EMT work synergistically to promote invasiveness during cancer progression.
9
Extent of EMT promotes invasive, contact-induced sliding on progressively narrower fiber-like tracks
TL;DR: It is demonstrated that EMT is a potent inducer of cell sliding, even under significant spatial constraints, and EMT-mediated invasive sliding is progressive, with partial EMT promoting intermediate sliding behavior, suggesting a model in which fiber maturation and partial E MT work synergistically to promote invasiveness during cancer progression.
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