Daniel DeSloover
University of Pennsylvania
5 Papers
1 Citations
Daniel DeSloover is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of Daniel DeSloover include Dow AgroSciences & Indiana University.
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Papers
THRUMIN1 is a light-regulated actin-bundling protein involved in chloroplast motility
Craig W. Whippo,Parul Khurana,Phillip A. Davis,Stacy L. DeBlasio,Daniel DeSloover,Christopher J. Staiger,Roger P. Hangarter +6 more
TL;DR: It is suggested that phototropin-induced actin bundling via THRUMIN1 is important for chloroplast movement, and studies of THRUMin1 will help elucidate the function of this family of eukaryotic proteins.
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Transcriptional activation of Brassica napus β‐ketoacyl‐ACP synthase II with an engineered zinc finger protein transcription factor
Manju Gupta,Russell Dekelver,Asha M. Palta,Carla Clifford,Sunita Gopalan,Jeffrey C. Miller,Stephen Novak,Daniel DeSloover,Daniel J Gachotte,James Patrick Connell,Josh Flook,Thomas G. Patterson,Kelly R. Robbins,Edward J. Rebar,Philip D. Gregory,Fyodor D. Urnov,Joseph F. Petolino +16 more
TL;DR: It is demonstrated that designed ZFP-TFs can be used to regulate the expression of endogenous genes to elicit specific phenotypic modifications of agronomically relevant traits in a crop species.
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A combinatorial bidirectional and bicistronic approach for coordinated multi-gene expression in corn
Sandeep Kumar,Diaa Alabed,John T. Whitteck,Wei Chen,Sara Bennett,Andrew Asberry,Xiujuan Wang,Daniel DeSloover,Murugesan Rangasamy,Terry R. Wright,Manju Gupta +10 more
TL;DR: This is the first report that demonstrates application of a single promoter for co-regulation of multiple genes in a crop plant and this stacking technology would be useful for engineering metabolic pathways both for basic and applied research.
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Abstract 4511: Characterization of tumor neoantigen repertoire in patients with germline BRCA1/2 mutations
Adam A. Kraya,Kara N. Maxwell,Brandon Wenz,Bradley Wubbenhorst,Daniel DeSloover,Nicole Lunceford,Jennifer J.D. Morrissette,Michael Feldman,Robert H. Vonderheide,Susan M. Domchek,Katherine L. Nathanson +10 more
TL;DR: The neoantigen repertoire in 20 breast and 19 ovarian tumors from patients with germline BRCA1/2 mutations is characterized, with positive correlates of neoantigens load in the authors' studies included mutational burden.
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Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas
Lauren Fishbein,Sanika Khare,Bradley Wubbenhorst,Daniel DeSloover,Kurt D'Andrea,Shana L. Merrill,Nam Woo Cho,Roger A. Greenberg,Tobias Else,Kathleen T. Montone,Virginia A. LiVolsi,Douglas L. Fraker,Robert Daber,Debbie L. Cohen,Katherine L. Nathanson +14 more
TL;DR: This finding suggests that loss of ATRX, a SWI/SNF chromatin remodeling protein, is important in the development of clinically aggressive pheochromocytomas and paragangliomas.