Daniel Allende
Duke University
6 Papers
289 Citations
Daniel Allende is an academic researcher from Duke University. The author has contributed to research in topics: Lipid bilayer & Melittin. The author has an hindex of 5, co-authored 5 publications.
Chat about Author
Papers
Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts.
TL;DR: These x-ray data provide accurate values for the widths of raft and nonraft bilayers that should be important in understanding mechanisms of protein sorting by rafts.
222
Bilayer interfacial properties modulate the binding of amphipathic peptides.
TL;DR: DeltaG degrees decreased linearly with increasing bilayer compressibility modulus, demonstrating the importance of bilayer mechanical properties in the binding of amphipathic peptides.
42
Jumping to rafts: gatekeeper role of bilayer elasticity
TL;DR: Both the partitioning of peptides into membranes and the distribution of transmembrane peptides in the plane of the membrane are modulated by physical properties of the lipid bilayer that are controlled by cholesterol content and the composition of the phospholipid hydrocarbon chain.
37
MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis
William J. Massey,Venkateshwari Varadharajan,Rakhee Banerjee,Amanda L. Brown,Anthony J. Horak,Rachel C. Hohe,Bryan M. Jung,Yunguang Qiu,Ernest R. Chan,Calvin Pan,Renliang Zhang,Daniel Allende,Belinda Willard,Feixiong Cheng,Aldons J. Lusis,Mark Brown +15 more
TL;DR: In this paper , the authors showed that MBOAT7 function in adipocytes contributes to diet-induced metabolic disturbances including hyperinsulinemia and systemic insulin resistance, and found that adipocyte-specific genetic deletion of Mboat7 is sufficient to promote hyperinulinemia and mild fatty liver.
10
Melittin-Induced Bilayer Leakage Depends on Lipid Material Properties: Evidence for Toroidal Pores
TL;DR: Results demonstrate the importance of bilayer material properties on melittin-induced leakage and indicate that the melittIn-induced pores are defects in the bilayer lined in part by lipid molecules.