Dan Wang
Nantong University
9 Papers
22 Citations
Dan Wang is an academic researcher from Nantong University. The author has contributed to research in topics: Microglia & Tail suspension test. The author has an hindex of 5, co-authored 8 publications.
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Papers
Antidepressive properties of microglial stimulation in a mouse model of depression induced by chronic unpredictable stress.
Zixuan Cai,Ting Ye,Xing Xu,Minhui Gao,Yaru Zhang,Dan Wang,Yiming Gu,Haojie Zhu,Lijuan Tong,Jiashu Lu,Zhuo Chen,Chao Huang +11 more
TL;DR: The results indicate that a single LPS injection displays rapid and sustained antidepressant effects in chronically stressed mice likely through stimulating hippocampal microglia.
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Apoptosis-triggered decline in hippocampal microglia mediates adolescent intermittent alcohol exposure-induced depression-like behaviors in mice.
Peili Hu,Dan Wang,Yaru Zhang,Zixuan Cai,Ting Ye,Lijuan Tong,Xing Xu,Jiashu Lu,Fengguo Liu,Xu Lu,Chao Huang +10 more
TL;DR: The results reveal a possible mechanism for AIE-induced depression and demonstrate that the restoration of hippocampal microglial homeostasis may be a therapeutic strategy for depression induced by alcohol intake and withdrawal.
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ERK1/2-dependent BDNF synthesis and signaling is required for the antidepressant effect of microglia stimulation
Xu Lu,Huijun Liu,Zixuan Cai,Zhichao Hu,Minxiu Ye,Yu Chen Gu,Yue Wang,Dan Wang,Qun Lu,Zhongxia Shen,Xinhua Shen,Chao-Cheng Huang +11 more
TL;DR: In this article , the role of BDNF-tyrosine kinase receptor B (TrkB) signaling in the effect of microglial stimulation in the dentate gyrus (DG) was investigated.
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Antidepressive properties of macrophage-colony stimulating factor in a mouse model of depression induced by chronic unpredictable stress.
TL;DR: It is demonstrated that M-CSF produces rapid and sustained antidepressant effects via the activation of the microglia in the hippocampus in a dose- and time-dependent manner.
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Identification of a microglial activation-dependent antidepressant effect of amphotericin B liposome.
Minhui Gao,Peili Hu,Zixuan Cai,Yue Wu,Dan Wang,Wenfeng Hu,Xing Xu,Yaru Zhang,Xu Lu,Dongjian Chen,Zhuo Chen,Kai Ma,Jie Wen,Hui Wang,Chao Huang +14 more
TL;DR: Results not only identify a novel pharmacological effect of amphotericin B liposome, but further support the notion that microglial activation in the hippocampus is a potential strategy for depression therapy.
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