Dan Li
24 Papers
Dan Li is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 14 publications.
Chat about Author
Papers
MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway
Keshan Zhang,Bo Yang,Chaochao Shen,Ting Zhang,Yu Hao,Dajun Zhang,Huanan Liu,Xijuan Shi,Guoli Li,Jinke Yang,Dan Li,Zixiang Zhu,Hong Tian,Fan Yang,Yi Ru,Weijun Cao,Jianhong Guo,Jijun He,Haixue Zheng,Xiangtao Liu +19 more
TL;DR: The results showed that MGF360-9L may help ASFV escape the host immunity by degrading STAT1 and STAT2 and thus inhibiting IFN-β signaling and is also an important virulence factor of AsFV.
74
African swine fever virus I267L acts as an important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity
Yong Ran,Dan Li,Mei-Guang Xiong,Huanan Liu,Tao Feng,Zhengwang Shi,Yuhua Li,Huang-Ning Wu,Su-Yun Wang,Haixue Zheng,Yan-Yi Wang +10 more
TL;DR: This study shows that the ASFV genome contains AT-rich regions that are recognized by the DNA-directed RNA polymerase III (Pol-III), leading to viral RNA sensor RIG-I-mediated innate immune responses.
Research progress on the proteins involved in African swine fever virus infection and replication
TL;DR: The main process of ASFV infection, replication and functions of related viral proteins, including 68 structural proteins and more than 100 non-structural proteins are summarized to provide scientific basis and theoretical basis for AsFV research and vaccine development.
African Swine Fever Virus Cysteine Protease pS273R Inhibits Type I Interferon Signaling by Mediating STAT2 Degradation
Yuhua Li,Jiang Peng,Zhi-Sheng Xu,Mei-Guang Xiong,Huang-Ning Wu,Su-Yun Wang,Dan Li,G. Zhu,Yong Ran,Yan-Yi Wang +9 more
TL;DR: In this paper , the authors identified ASFV cysteine protease pS273R as an antagonist of type I interferon (IFN) triggered by type I IFNs.
17
Peste Des Petits Ruminants Virus N Protein Is a Critical Proinflammation Factor That Promotes MyD88 and NLRP3 Complex Assembly
Lingxia Li,Wenping Yang,Xiaoxiao Ma,Jinyan Wu,Xiaodong Qin,Xiaoyan Cao,Jian Hua Zhou,Li Jin,Jijun He,Haixue Zheng,Xiangtao Liu,Dan Li,Youjun Shang +12 more
TL;DR: This study showed that PPRV induced the secretion of interleukin 1β (IL-1β) by activating the NF-κB signaling pathway and the NLRP3 inflammasome and demonstrated a new function of P PRV N protein as an important proinflammation factor and identify a novel underlying mechanism modulating inflammaome assembly and function induced by PPRv.
12