Dalip Sethi
University of Delhi
27 Papers
107 Citations
Dalip Sethi is an academic researcher from University of Delhi. The author has contributed to research in topics: Biochip & Medicine. The author has an hindex of 10, co-authored 22 publications. Previous affiliations of Dalip Sethi include Institute of Genomics and Integrative Biology & Indian Institute of Toxicology Research.
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Papers
Effects of hypoxanthine substitution in peptide nucleic acids targeting KRAS2 oncogenic mRNA molecules: theory and experiment.
Jeffrey M. Sanders,Matthew E. Wampole,Chang-Po Chen,Dalip Sethi,Amrita Singh,François-Yves Dupradeau,Fan Wang,Brian D. Gray,Mathew L. Thakur,Eric Wickstrom +9 more
TL;DR: In this paper, a PNA dodecamer incorporating hypoxanthine, which can form Watson-Crick base pairs with adenine, cytosine, thymine, and uracil, was used for radioimaging of mutant KRAS2 mRNA in tumors in mice.
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Fluorescent Peptide–PNA Chimeras for Imaging Monoamine Oxidase A mRNA in Neuronal Cells
TL;DR: The synthesis, characterization, and in vitro evaluation of novel fluorescent peptide-peptide nucleic acid (PNA) chimeras for MAOA mRNA imaging in live neuronal cells showed promise in enabling real time imaging and quantitation of neuronal mRNAs in live animal models.
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Construction of oligonucleotide microarrays (biochips) via thioether linkage for the detection of bacterial meningitis.
TL;DR: A method that allows the direct immobilization of thiolated oligonucleotides onto an epoxy-activated glass surface via a stable thioether linkage under microwaves is reported, which indicates that the chemistry can be used in integrated PCR/microarray devices.
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A facile method for the construction of oligonucleotide microarrays.
TL;DR: A facile protocol for the construction of an oligonucleotide microarray is demonstrated that involves immobilization of oligon nucleotide-trimethoxysilyl conjugates onto virgin glass microslides for detection of bacterial meningitis.
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N-(Iodoacetyl)-N'-(anthraquinon-2-oyl)-ethylenediamine (IAED): a new heterobifunctional reagent for the preparation of biochips.
Satyakam Patnaik,Archana Swami,Dalip Sethi,Atul Pathak,Bhagwan S. Garg,K.C. Gupta,Pradeep Kumar +6 more
TL;DR: The design and synthesis of a new heterobifunctional reagent, N-(iodoacetyl)-N'-(anthraquinon-2-oyl)-ethylenediamine (IAED), have been described for the preparation of oligonucleotide-based biochips and were found to be thermally stable.
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