Daisuke Segawa
Akita University
12 Papers
168 Citations
Daisuke Segawa is an academic researcher from Akita University. The author has contributed to research in topics: Hepatic stellate cell & Portal hypertensive gastropathy. The author has an hindex of 11, co-authored 12 publications.
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Papers
Genipin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of TNF-α production
Satoko Takeuchi,Takashi Goto,Ken-ichiro Mikami,Kouichi Miura,Shigetoshi Ohshima,Kazuo Yoneyama,Michiko Sato,Tomomi Shibuya,Daisuke Watanabe,Ei Kataoka,Daisuke Segawa,Ayako Endo,Wataru Sato,Ryutaro Yoshino,Sumio Watanabe +14 more
TL;DR: Genipin, a metabolite derived from the herbal medicine Inchinko-to improved acute liver dysfunction by suppressive effect of TNF-alpha production in vivo and in vitro, and was significantly suppressed by genipin administration.
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Efficacy of contrast-enhanced ultrasonography in radiofrequency ablation for hepatocellular carcinoma.
Takahiro Dohmen,Ei Kataoka,Ikuhiro Yamada,Kouichi Miura,Shigetoshi Ohshima,Tomomi Shibuya,Daisuke Segawa,Wataru Sato,Yumiko Anezaki,Hajime Ishii,Kentaro Kamada,Takashi Goto,Hirohide Ohnishi +12 more
TL;DR: The ability of CE-US with Sonazoid(®) to detect an accurate area of HCC before RFA and to immediately detect a residual tumor during RFA might contribute to an increase of the radicality and reduction of local recurrence after RFA.
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Zinc L-carnosine protects against mucosal injury in portal hypertensive gastropathy through induction of heat shock protein 72
Ken-ichiro Mikami,Michiro Otaka,Daisuke Watanabe,Takashi Goto,Ayako Endoh,Kouichi Miura,Shigetoshi Ohshima,Kazuo Yoneyama,Michiko Sato,Tomomi Shibuya,Daisuke Segawa,Ei Kataoka,Ryutaro Yoshino,Satoko Takeuchi,Wataru Sato,Masaru Odashima,Sumio Watanabe +16 more
TL;DR: The effects of zinc L‐carnosine, an anti‐ulcer drug, were evaluated on expression of heat shock protein (hsp) 72 and cytoprotection in gastric mucosa in a rat model of PHG.
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Expression of a 72-kDa heat shock protein, and its cytoprotective function, in gastric mucosa in cirrhotic rats.
Daisuke Watanabe,Michiro Otaka,Ken-ichiro Mikami,Kazuo Yoneyama,Takashi Goto,Kouichi Miura,Shigetoshi Ohshima,Jiun-Guey Lin,Tomomi Shibuya,Daisuke Segawa,Ei Kataoka,Noriaki Konishi,Masaru Odashima,Masashiro Sugawara,Sumio Watanabe +14 more
TL;DR: Findings suggest that H SP72 in the gastric mucosa plays a crucial role with respect to cytoprotection; the induction of HSP72 may provide therapeutic strategies for protection against mucosal injury in PHG.
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Induction of a 72-kDa heat shock protein and protection against lipopolysaccharide-induced liver injury in cirrhotic rats.
Ken-ichiro Mikami,Michiro Otaka,Takashi Goto,Kouichi Miura,Shigetoshi Ohshima,Kazuo Yoneyama,Jiun-Guey Lin,Daisuke Watanabe,Daisuke Segawa,Ei Kataoka,Masaru Odashima,Sumio Watanabe +11 more
TL;DR: This study investigated the cytoprotective effect of HSP72 on lipopolysaccharide‐induced liver injury in carbon tetrachloride (CCl4)‐induced cirrhotic rats.
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