Daisuke Isojima
Yokohama City University
8 Papers
12 Citations
Daisuke Isojima is an academic researcher from Yokohama City University. The author has contributed to research in topics: Dementia with Lewy bodies & Dementia. The author has an hindex of 6, co-authored 8 publications.
Chat about Author
Papers
Clinical Features of Argyrophilic Grain Disease: A Retrospective Survey of Cases With Neuropsychiatric Symptoms
Takashi Togo,Daisuke Isojima,Hiroyasu Akatsu,Kyoko Suzuki,Hirotake Uchikado,Omi Katsuse,Eizo Iseki,Kenji Kosaka,Yoshio Hirayasu +8 more
TL;DR: AGD is a late-onset dementing disorder clinically characterized by amnesia, with other cognitive functions relatively spared, and prominent neuropsychiatric features that may correlate with the high level of AGD seen in limbic structures.
62
Depletion of cholinergic neurons in the nucleus of the medial septum and the vertical limb of the diagonal band in dementia with Lewy bodies
Hiroshige Fujishiro,Hiroyuki Umegaki,Daisuke Isojima,Hiroyasu Akatsu,Akihisa Iguchi,Kenji Kosaka +5 more
TL;DR: Cholinergic neurons of the Ch1-2 regions are more severely affected in DLB than in AD, which suggests a possibility that hippocampal cholinergic projection is involved in Lewy-related neurites in the CA2–3 regions, the origin of which remains unclear.
54
Non-uniformity in the regional pattern of Lewy pathology in brains of dementia with Lewy bodies.
Ryoko Yamamoto,Eizo Iseki,Wami Marui,Takashi Togo,Omi Katsuse,Masanori Kato,Daisuke Isojima,Hiroyasu Akatsu,Kenji Kosaka,Heii Arai +9 more
TL;DR: It is suggested that PD has clinico‐pathological continuity with DLB, and that the regional pattern of Lewy pathology is not uniform, which suggests the possibility thatLewy pathology of the limbic type/pure and common forms mainly progresses from the brainstem to the cerebrum, whereas that of the neocortical type/common and AD forms mainly progressing from the cere brum to the brain stem.
28
Vascular complications in dementia with Lewy bodies: A postmortem study
Daisuke Isojima,Takashi Togo,Kenji Kosaka,Hiroshige Fujishiro,Hiroyasu Akatsu,Omi Katsuse,Shuji Iritani,Toshihiko Matsumoto,Yoshio Hirayasu +8 more
TL;DR: It is suggested that grossly identified hemorrhages are more common inDLB because of trauma, while microinfarcts are less common in DLB than AD, although the reason remains unclear.
19
Clinical profiles of autopsy-confirmed dementia with Lewy bodies at institutionalization: Comparison with Alzheimer’s disease
Hiroshige Fujishiro,Hiroyuki Umegaki,Yusuke Suzuki,Daisuke Isojima,Hiroyasu Akatsu,Hiroyuki Ikari,Akihisa Iguchi,Kenji Kosaka +7 more
TL;DR: This study was carried out to clarify whether there are any differences in the symptoms that required institutionalization between patients with DLB and those with AD.
7