Dai Cui
Nanjing Medical University
5 Papers
25 Citations
Dai Cui is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Thyroid cancer & Cancer cell. The author has an hindex of 3, co-authored 5 publications.
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Papers
Inhibitory effects of retinoic acid on invasiveness of human thyroid carcinoma cell lines in vitro.
TL;DR: The influence of ATRA is demonstrated on both important determinants of metastatic behavior (“de-adhesion” and proteolysis) in thyroid carcinoma cell lines, especially in anaplastic cancer cells, which may add to the explanations for beneficial effects of RA in the treatment of metastasis thyroid carcinomas.
25
Inhibiting β-catenin expression promotes efficiency of radioiodine treatment in aggressive follicular thyroid cancer cells probably through mediating NIS localization
Ling Lan,Spyros Basourakos,Dai Cui,Xuemei Zuo,Wei Deng,Lili Huo,Linghai Chen,Guoying Zhang,Li-li Deng,Bing-Yin Shi,Yong Luo +10 more
TL;DR: In this paper, the authors investigated whether the efficacy of radioiodine therapy towards aggressive thyroid cancer cells was affected by β-catenin activity and associated with sodium/iodine symporter (NIS) localization.
18
ATRA increases iodine uptake and inhibits the proliferation and invasiveness of human anaplastic thyroid carcinoma SW1736 cells: Involvement of β-catenin phosphorylation inhibition.
Ling Lan,Spyros Basourakos,Dai Cui,Xuemei Zuo,Wei Deng,Lili Huo,Hailing Chen,Guoying Zhang,Li-li Deng,Bingyin Shi,Yong Luo +10 more
TL;DR: ATRA could be used to improve the isotope sensitivity of ATC by increasing the iodine uptake and inhibited the proliferation and invasion of SW1736 cells, involving β-catenin phosphorylation.
[β-catenin nuclear translocation represses thyroid cancer stem cells differentiating into cells with sodium-iodine symporter functional expression].
TL;DR: Induction of β-catenin nuclear translocation in stem cells may generate differentiated thyroid cancer cells that are not sensitive to radioiodine treatment.
1
Epithelial-mesenchymal transition triggers cancer stem cell generation in human thyroid cancer cells.
Ling Lan,Yong Luo,Dai Cui,Bing-Yin Shi,Wei Deng,Li-Li Huo,Hai-Ling Chen,Guo-Ying Zhang,Li-Li Deng +8 more
TL;DR: Results indicate that E MT induction promotes CSC traits and cell proportions in the thyroid cancer cells, which implies that EMT could induce cancer stem cell generation and tumor progression in thyroid cancers.